Detailed information NTG1128223

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: WDLP6_RS05840
• Genome accession: NZ_LR594671
• Coordinates: 1206270..1207124 (-)
• Length: 284 a.a.
• NCBI ID: WP_162591590.1
• Uniprot ID: A0A6P2EBU3
• Organism: Variovorax sp. PBL-E5
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1201270..1212124

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WDLP6_RS05810 (E5CHR_01160)	-	1201554..1201985 (+)	432	WP_174259848.1	NUDIX domain-containing protein	-
WDLP6_RS05815 (E5CHR_01161)	-	1201979..1202188 (-)	210	WP_162566221.1	DNA gyrase inhibitor YacG	-
WDLP6_RS05820 (E5CHR_01162)	zapD	1202262..1203017 (-)	756	WP_162566222.1	cell division protein ZapD	-
WDLP6_RS05825 (E5CHR_01163)	-	1203054..1204070 (-)	1017	WP_162591587.1	hypothetical protein	-
WDLP6_RS05830 (E5CHR_01164)	-	1204079..1205575 (-)	1497	WP_162591588.1	MBOAT family protein	-
WDLP6_RS05835 (E5CHR_01165)	coaE	1205657..1206256 (-)	600	WP_162591589.1	dephospho-CoA kinase	-
WDLP6_RS05840 (E5CHR_01166)	pilD	1206270..1207124 (-)	855	WP_162591590.1	A24 family peptidase	Machinery gene
WDLP6_RS05845 (E5CHR_01167)	pilC	1207124..1208347 (-)	1224	WP_162566227.1	type II secretion system F family protein	Machinery gene
WDLP6_RS05850 (E5CHR_01168)	pilB	1208368..1210101 (-)	1734	WP_162591591.1	type IV-A pilus assembly ATPase PilB	Machinery gene
WDLP6_RS05860 (E5CHR_01170)	-	1210333..1211325 (-)	993	WP_162566229.1	polyprenyl synthetase family protein	-
WDLP6_RS05865 (E5CHR_01171)	rplU	1211512..1211823 (+)	312	WP_162566230.1	50S ribosomal protein L21	-
WDLP6_RS05870 (E5CHR_01172)	rpmA	1211836..1212093 (+)	258	WP_162566231.1	50S ribosomal protein L27	-

Sequence

Protein

• Length: 284 a.a.
• Molecular weight: 30160.71 Da
• Isoelectric Point: 7.8830

>NTDB_id=1128223 WDLP6_RS05840 WP_162591590.1 1206270..1207124(-) (pilD) [Variovorax sp. PBL-E5]
MLVSQGVDAALAGVFGLLIGSFLNVVIHRLPKMLERQWAAECASAGGADAAAAAKDAEAFNLMVPHSRCPQCGHVIRWYE
NVPVLSYLFLRGRCSACKTPISLRYPVVELVTGALFAWCVWRMPGQFGSLAWCGFAAALLALALIDWDTTLLPDDITLPL
LWAGLLAAIAGFTGVTLVNAVWGAVAGYGSLWAIYWLFKLTTGKEGMGYGDFKLFAAFGAWFGWQALVPIILMASVIGVI
VGIALKLGKGLREGGYVPFGPFLAGAGFTAMIFGPDAILRVAGL

Nucleotide

• Length: 855 bp

>NTDB_id=1128223 WDLP6_RS05840 WP_162591590.1 1206270..1207124(-) (pilD) [Variovorax sp. PBL-E5]
ATGCTGGTTTCGCAGGGGGTCGACGCCGCACTGGCCGGCGTGTTCGGGTTGTTGATCGGCAGTTTCCTCAACGTCGTGAT
CCATCGCCTGCCGAAGATGCTGGAGCGGCAATGGGCCGCCGAATGCGCGAGCGCCGGCGGCGCGGATGCCGCGGCCGCGG
CAAAGGACGCCGAAGCTTTCAACCTGATGGTTCCCCACTCGCGCTGCCCGCAGTGCGGCCATGTCATCCGCTGGTACGAG
AACGTCCCCGTCCTGAGCTACCTGTTCCTGCGCGGCCGATGTTCCGCGTGCAAGACCCCCATCAGCCTGCGCTATCCGGT
GGTCGAACTGGTGACCGGTGCGCTCTTCGCATGGTGTGTGTGGCGCATGCCCGGTCAGTTCGGCAGTCTGGCCTGGTGTG
GGTTCGCCGCGGCGCTTCTTGCGCTGGCGCTGATCGACTGGGACACGACGCTTCTGCCGGACGACATCACGCTGCCGCTG
CTGTGGGCCGGCCTGCTGGCCGCCATCGCCGGCTTCACGGGCGTGACGCTCGTCAATGCCGTCTGGGGTGCCGTGGCGGG
CTACGGGTCGCTGTGGGCCATCTACTGGCTGTTCAAGCTGACCACCGGCAAGGAAGGCATGGGCTATGGCGACTTCAAGC
TGTTTGCCGCCTTCGGCGCATGGTTCGGATGGCAGGCCCTGGTGCCGATCATCCTCATGGCCTCGGTGATCGGCGTGATC
GTCGGCATCGCGCTCAAACTCGGCAAGGGCTTGCGCGAGGGCGGCTACGTGCCCTTCGGTCCGTTCCTGGCGGGCGCGGG
CTTCACGGCCATGATCTTCGGTCCGGACGCGATCCTTCGCGTGGCAGGTCTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (14-122)

• Type IV leader peptidase family (Peptidase_A24) (135-243)

3D structure

• AlphaFold DB: A0A6P2EBU3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	51.673	94.718	0.489
pilD	Vibrio campbellii strain DS40M4	49.813	94.014	0.468
pilD	Acinetobacter baumannii D1279779	45.387	95.423	0.433
pilD	Neisseria gonorrhoeae MS11	46.388	92.606	0.43
pilD	Acinetobacter nosocomialis M2	44.649	95.423	0.426