Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FGL23_RS02960 Genome accession   NZ_LR594049
Coordinates   635374..636675 (+) Length   433 a.a.
NCBI ID   WP_061603672.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 630374..641675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS02935 (NCTC10231_00584) - 631117..631749 (+) 633 WP_061603669.1 response regulator transcription factor -
  FGL23_RS02940 (NCTC10231_00585) - 631837..633240 (+) 1404 WP_061603670.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGL23_RS02945 (NCTC10231_00586) - 633237..633623 (+) 387 WP_060552930.1 S1 RNA-binding domain-containing protein -
  FGL23_RS02950 (NCTC10231_00587) cysK 633659..634588 (-) 930 WP_061603671.1 cysteine synthase A -
  FGL23_RS02955 (NCTC10231_00588) - 634686..635318 (-) 633 WP_045772978.1 YigZ family protein -
  FGL23_RS02960 (NCTC10231_00589) comFA/cflA 635374..636675 (+) 1302 WP_061603672.1 DEAD/DEAH box helicase Machinery gene
  FGL23_RS02965 (NCTC10231_00590) comFC/cflB 636672..637337 (+) 666 WP_138115419.1 ComF family protein Machinery gene
  FGL23_RS02970 (NCTC10231_00591) hpf 637422..637964 (+) 543 WP_012000104.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49483.55 Da        Isoelectric Point: 8.8096

>NTDB_id=1127955 FGL23_RS02960 WP_061603672.1 635374..636675(+) (comFA/cflA) [Streptococcus gordonii strain NCTC10231]
MLELQDCLGRIFTKEQLPPELLKKAKRLSSIFEKKGELFCSRCYSQIDKERNLLPIGAYYCRECILLGRVRSDEDLYYFF
QESFPIISSLKWLGQLTEYQERVSKGLLEGVQSKQDTLVHAVTGAGKTEMIYQVVAQMLDQGGAVCIASPRIDVCLELYR
RLKEDFSCDISLLHGESDPYSRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPVLYHAVEQAVKNEGTTIFLTATS
TDELDKKVQKGILKRLSLPRRFHGNPLIIPQKVWLSGLNKDLQREKLPAKLVKYLRKQRKTKFPLLIFASEIKKGQEIKQ
VLQKYFPEENVGFVASTTENRLKIVQDFRDKKISILVTTTILERGVTFPCVDVIVLEANHRLFTRSALVQIGGRVGRSME
RPTGDLIFFHDGTNIQIEKAINEIKAMNREAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1127955 FGL23_RS02960 WP_061603672.1 635374..636675(+) (comFA/cflA) [Streptococcus gordonii strain NCTC10231]
ATGTTGGAATTGCAAGATTGTTTAGGGCGAATTTTTACTAAAGAACAGTTACCTCCTGAACTACTTAAGAAAGCTAAAAG
ACTATCATCAATTTTTGAAAAAAAGGGAGAACTCTTTTGTTCTCGCTGCTACAGTCAGATTGATAAGGAAAGAAATTTAT
TACCAATTGGTGCATATTATTGCAGAGAATGCATTCTTCTAGGGAGAGTGCGTAGTGACGAAGATCTTTATTATTTTTTT
CAAGAATCTTTTCCTATAATATCAAGTTTGAAATGGCTCGGCCAATTGACAGAATATCAGGAAAGAGTTTCTAAGGGATT
ACTTGAAGGAGTGCAAAGTAAACAGGATACTTTAGTCCACGCTGTAACTGGAGCAGGAAAAACGGAAATGATCTATCAAG
TGGTTGCTCAGATGTTAGATCAAGGAGGGGCTGTCTGTATAGCTAGTCCTCGGATAGATGTCTGTTTGGAACTTTACCGG
CGTTTAAAAGAAGATTTTTCATGTGATATTTCCCTATTGCATGGGGAGTCCGACCCCTATTCACGCAGTCCCTTAGTGAT
TGCAACAACTCATCAATTACTAAAATTTTATCAGGCATTTGATTTACTCATTGTTGATGAGGTAGATGCCTTTCCTTATG
TAGATAACCCTGTGCTCTATCATGCTGTCGAGCAAGCAGTAAAAAATGAAGGAACTACAATATTCCTAACGGCTACGTCA
ACTGATGAGCTTGATAAAAAAGTCCAAAAAGGAATTTTAAAGAGGTTAAGTTTGCCAAGACGCTTTCATGGAAATCCCTT
GATTATCCCACAAAAAGTATGGCTTTCTGGTCTAAATAAAGACCTCCAAAGAGAAAAACTACCAGCCAAGTTAGTCAAGT
ATCTTAGAAAACAAAGAAAAACAAAATTCCCACTCTTAATTTTTGCTTCAGAAATTAAAAAAGGGCAGGAGATAAAGCAA
GTCTTACAAAAATATTTTCCAGAAGAAAATGTAGGTTTTGTAGCTTCTACAACGGAAAATAGATTAAAAATAGTGCAAGA
TTTTCGAGATAAAAAGATAAGTATATTAGTAACAACTACAATTTTAGAAAGAGGGGTTACTTTTCCCTGTGTAGATGTAA
TTGTTTTAGAAGCTAACCATCGTCTCTTTACAAGGAGTGCTTTAGTACAAATTGGCGGGCGAGTAGGAAGAAGTATGGAA
CGACCGACAGGTGACTTGATATTTTTCCATGATGGCACTAATATACAGATAGAAAAAGCAATCAATGAGATTAAAGCAAT
GAATAGAGAGGCCGGATTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(97-245)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

68.224

98.845

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

68.224

98.845

0.674
  comFA/cflA Streptococcus pneumoniae D39

68.224

98.845

0.674
  comFA/cflA Streptococcus pneumoniae R6

68.224

98.845

0.674
  comFA/cflA Streptococcus mitis NCTC 12261

68.075

98.383

0.67
  comFA/cflA Streptococcus mitis SK321

68.075

98.383

0.67
  comFA Lactococcus lactis subsp. cremoris KW2

53.807

90.993

0.49
  comFA Latilactobacillus sakei subsp. sakei 23K

39.492

100

0.395

Multiple sequence alignment