Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   FGL18_RS04510 Genome accession   NZ_LR594046
Coordinates   912690..913919 (+) Length   409 a.a.
NCBI ID   WP_003054192.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 907690..918919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS04485 (NCTC6403_00924) - 908310..909587 (-) 1278 WP_138125397.1 hydroxymethylglutaryl-CoA reductase, degradative -
  FGL18_RS04490 (NCTC6403_00925) - 909568..910749 (-) 1182 WP_138125399.1 hydroxymethylglutaryl-CoA synthase -
  FGL18_RS04495 (NCTC6403_00926) - 910967..911806 (+) 840 WP_129555803.1 thymidylate synthase -
  FGL18_RS04500 (NCTC6403_00927) - 911887..912384 (+) 498 WP_065957460.1 dihydrofolate reductase -
  FGL18_RS04505 (NCTC6403_00928) - 912404..912574 (+) 171 WP_003054200.1 hypothetical protein -
  FGL18_RS04510 (NCTC6403_00929) clpX 912690..913919 (+) 1230 WP_003054192.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  FGL18_RS04515 (NCTC6403_00930) yihA 913929..914528 (+) 600 WP_138125401.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  FGL18_RS04520 (NCTC6403_00931) - 914672..915415 (+) 744 WP_138125403.1 hypothetical protein -
  FGL18_RS04525 (NCTC6403_00932) clpC 915472..917571 (-) 2100 WP_138125405.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FGL18_RS04530 (NCTC6403_00935) rplJ 918340..918840 (+) 501 WP_003050354.1 50S ribosomal protein L10 -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45060.54 Da        Isoelectric Point: 4.5866

>NTDB_id=1127802 FGL18_RS04510 WP_003054192.1 912690..913919(+) (clpX) [Streptococcus dysgalactiae strain NCTC6403]
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1127802 FGL18_RS04510 WP_003054192.1 912690..913919(+) (clpX) [Streptococcus dysgalactiae strain NCTC6403]
ATGGCAGGAAATCGTACAAACGATATTAAAGTATATTGCTCATTTTGTGGCAAGAGCCAAGACGAAGTCAAAAAAATTAT
TGCAGGGAATAATGTTTTTATCTGTAATGAATGTGTGGCTTTGTCACAAGAAATTATTAAAGAAGAGTTGGCAGAAGAAG
TGTTAGCTGACCTGACAGAAGTTCCAAAACCAAAAGAACTCCTTGAGGTCTTAAACCAGTATGTTGTTGGCCAAGATCGT
GCCAAACGTGCTTTATCAGTAGCTGTTTACAATCATTACAAACGCGTGTCATTCACGGAAAGTCGTGATGATGAAGATGT
TGAATTGCAAAAATCAAACATTTTAATGATTGGTCCAACAGGTTCAGGAAAGACTTTTCTCGCTCAAACCTTAGCTAAGA
GCTTAAATGTTCCTTTTGCGATTGCTGATGCAACCTCACTGACTGAAGCAGGTTATGTTGGAGAAGATGTGGAAAATATT
CTTCTCAAGCTTATCCAAGCAGCTGATTATAATGTGGAACGAGCAGAGCGTGGTATCATCTATGTCGATGAAATTGATAA
GATTGCTAAAAAAGGTGAAAATGTGTCCATCACACGTGATGTTTCTGGTGAGGGAGTTCAACAGGCCTTGCTAAAAATCA
TTGAAGGAACGGTTGCTAGTGTTCCTCCTCAAGGCGGTCGTAAGCATCCAAATCAGGAAATGATTCAAATTGATACCAAG
AATATCTTGTTTATTGTTGGGGGAGCCTTTGATGGCATTGAAGACATTGTCAAACAACGTTTAGGAGAAAAAGTCATTGG
TTTTGGTCAAAACAGCCGAAAAATCGATGACAATGCTTCTTATATGCAAGAGATTATTTCAGAAGATATCCAAAAATTTG
GTCTTATCCCAGAGTTTATTGGACGCTTGCCAGTCGTAGCTGCTCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAGCCAAGAAATGCCCTAGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGTGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAGCGTAAGACAGGCGCGCGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.487

100

0.895
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.853

98.044

0.577

Multiple sequence alignment