Detailed information NTG1127803

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FGL18_RS04525
• Genome accession: NZ_LR594046
• Coordinates: 915472..917571 (-)
• Length: 699 a.a.
• NCBI ID: WP_138125405.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain NCTC6403
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 910472..922571

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL18_RS04495 (NCTC6403_00926)	-	910967..911806 (+)	840	WP_129555803.1	thymidylate synthase	-
FGL18_RS04500 (NCTC6403_00927)	-	911887..912384 (+)	498	WP_065957460.1	dihydrofolate reductase	-
FGL18_RS04505 (NCTC6403_00928)	-	912404..912574 (+)	171	WP_003054200.1	hypothetical protein	-
FGL18_RS04510 (NCTC6403_00929)	clpX	912690..913919 (+)	1230	WP_003054192.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
FGL18_RS04515 (NCTC6403_00930)	yihA	913929..914528 (+)	600	WP_138125401.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FGL18_RS04520 (NCTC6403_00931)	-	914672..915415 (+)	744	WP_138125403.1	hypothetical protein	-
FGL18_RS04525 (NCTC6403_00932)	clpC	915472..917571 (-)	2100	WP_138125405.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGL18_RS04530 (NCTC6403_00935)	rplJ	918340..918840 (+)	501	WP_003050354.1	50S ribosomal protein L10	-
FGL18_RS04535 (NCTC6403_00936)	rplL	918905..919270 (+)	366	WP_003043797.1	50S ribosomal protein L7/L12	-
FGL18_RS04540 (NCTC6403_00937)	pbp3	919508..920737 (+)	1230	WP_138125407.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
FGL18_RS04545 (NCTC6403_00938)	-	920834..921796 (-)	963	WP_138125409.1	polysaccharide deacetylase family protein	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77438.12 Da
• Isoelectric Point: 4.8927

>NTDB_id=1127803 FGL18_RS04525 WP_138125405.1 915472..917571(-) (clpC) [Streptococcus dysgalactiae strain NCTC6403]
MTNYYDKDPFGNMDDIFNQLMGNMGGYRSENRRYLVNGREMTPEEFQAYRQTGRLSDKGTEQPTSQGHQTKKDGILAKLG
TNLTEEARQGKLDPVIGRNHEIQDTAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENIQNMIQEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADMLKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDTVLKAAIDYSIQYIPQRSLPDKAIDLVDMTAAHLAA
QHPVTDLKSLEAEMTTQKNIQEEAVAKEDFERALTAKTRIEELQKQMNNHSEDQKVTATVNDIAESVERLTGVPVSNMGA
SDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKEAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGHQEDENTDQPAIMDRIAPYFRPEFLNRFNGVIEFNHLQKEDLEEIVDLMLAEVNQTIAKKGISLTISDD
AKAHLIELGYDHAMGVRPLRRVIEQEIRDRITDFYLDHPEVKNLQASLEQGQLVIHDKN

Nucleotide

• Length: 2100 bp

>NTDB_id=1127803 FGL18_RS04525 WP_138125405.1 915472..917571(-) (clpC) [Streptococcus dysgalactiae strain NCTC6403]
ATGACAAATTATTATGACAAAGATCCTTTTGGAAACATGGATGATATCTTTAATCAACTAATGGGCAATATGGGTGGCTA
TCGCAGTGAAAATCGACGCTATTTAGTGAACGGACGCGAAATGACACCTGAAGAATTCCAGGCATATCGTCAAACTGGAC
GTCTGAGCGATAAAGGTACTGAACAACCTACATCCCAAGGTCATCAGACCAAAAAGGATGGGATTTTAGCTAAACTTGGC
ACCAACTTAACGGAAGAAGCAAGACAAGGAAAACTTGATCCTGTTATTGGTCGCAATCACGAAATTCAAGACACTGCGGA
AATTTTAGCTCGCCGAACAAAGAATAATCCTGTTCTAGTCGGAGATGCTGGTGTTGGTAAAACAGCTGTGGTTGAAGGGC
TAGCTCAAGCTATTGTGAATGGTGACGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCCATTGATATTTCTGGCCTT
GAAGCAGGCACTCAGTACCGTGGCTCCTTTGAAGAAAATATCCAAAACATGATTCAAGAGGTTAAAGAAGCTGGGAATAT
TATTCTCTTCTTTGACGAAATCCATCAAATCCTTGGTGCAGGTTCTACTGGTGGTGACTCTGGGTCTAAAGGATTAGCTG
ATATGCTAAAACCTGCTCTTTCCCGTGGTGAATTGACACTGATTGGTGCCACAACTCAAGATGAATACCGCAATACCATT
TTAAAAAATGCTGCGCTTGCTCGTCGTTTTAATGAGGTTAAGGTAAACGCACCGTCTGCTGAGGACACCTTCCATATTTT
AATGGGAATCCGAAATCTTTACGAACAACACCATAATGTTATCCTTCCGGATACTGTTCTTAAAGCTGCGATTGACTATT
CTATTCAGTACATTCCTCAACGTAGTTTACCAGATAAAGCGATTGACTTAGTAGATATGACTGCTGCGCATTTAGCTGCT
CAGCATCCTGTGACTGACCTCAAGTCTCTAGAAGCTGAAATGACCACTCAAAAGAATATCCAAGAAGAGGCTGTGGCTAA
GGAAGATTTTGAGAGAGCTTTAACCGCTAAAACTCGAATTGAAGAATTGCAAAAACAAATGAACAACCATAGCGAAGACC
AAAAGGTTACTGCTACTGTCAATGACATTGCAGAATCTGTAGAGCGCCTGACTGGTGTCCCAGTGTCCAATATGGGAGCT
AGTGATTTGGAAAGACTCAAAGAAATTAGCAACCGCTTAAAAGGACACGTGATTGGCCAAGATGGAGCTGTTGAAGCTGT
GGCTCGTGCTATTCGCCGTAATCGAGCTGGTTTTGATGACGGCAATCGTCCTATCGGTTCCTTCCTCTTTGTTGGACCAA
CAGGTGTTGGTAAGACAGAATTAGCCAAACAGCTAGCACTGGACCTCTTTGGTTCCAAAGAGGCTATTATTCGACTTGAC
ATGTCCGAATACAGTGATCGTACCGCTGTGTCCAAGCTAATAGGGACAACTGCCGGTTATGTCGGTTATGATGATAATAA
CAATACGTTAACGGAACGTGTTCGTCGCAACCCGTATGCGATTGTTCTATTGGATGAGATTGAAAAAGCCGATCCGCAAG
TCATTACCCTTCTTCTCCAAGTACTAGATGATGGCCGATTAACAGATGGTCAGGGAAATACCATCAACTTTAAAAACACT
GTTATCATTGCTACTTCTAATGCTGGATTTGGGCATCAAGAAGATGAAAATACTGATCAACCTGCTATTATGGACCGTAT
TGCGCCTTACTTTAGACCAGAGTTTCTCAATCGTTTCAATGGGGTTATCGAATTCAATCATCTGCAAAAAGAAGACTTAG
AAGAAATTGTTGATTTAATGTTAGCGGAAGTTAATCAAACTATAGCTAAAAAAGGGATCAGCTTAACTATCTCTGATGAT
GCTAAAGCTCACTTGATTGAATTAGGTTATGACCACGCAATGGGAGTTCGACCATTACGCCGTGTCATCGAGCAAGAAAT
CCGAGACCGCATTACAGACTTTTACCTCGATCACCCAGAGGTCAAAAACCTACAAGCTAGTCTGGAACAAGGACAGTTAG
TCATTCACGACAAAAACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (259-353)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-679)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.532	100	0.482
clpE	Streptococcus mutans UA159	46.544	100	0.472
clpE	Streptococcus pneumoniae Rx1	45.768	99.714	0.456
clpE	Streptococcus pneumoniae D39	45.768	99.714	0.456
clpE	Streptococcus pneumoniae R6	45.768	99.714	0.456
clpE	Streptococcus pneumoniae TIGR4	45.69	99.571	0.455
clpC	Bacillus subtilis subsp. subtilis str. 168	44.341	92.275	0.409
clpC	Streptococcus pneumoniae D39	40.943	97.139	0.398
clpC	Streptococcus pneumoniae Rx1	40.943	97.139	0.398
clpC	Streptococcus pneumoniae TIGR4	40.795	97.139	0.396
clpC	Streptococcus thermophilus LMG 18311	42.903	88.698	0.381
clpC	Streptococcus mutans UA159	42.742	88.698	0.379
clpC	Streptococcus thermophilus LMD-9	42.718	88.412	0.378
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.165	88.555	0.373