Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FGL16_RS02390 Genome accession   NZ_LR594043
Coordinates   430878..432170 (+) Length   430 a.a.
NCBI ID   WP_014735513.1    Uniprot ID   -
Organism   Streptococcus suis strain NCTC10237     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 425878..437170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL16_RS02365 (NCTC10237_00446) - 426682..427323 (+) 642 WP_014735510.1 response regulator transcription factor -
  FGL16_RS02370 (NCTC10237_00447) - 427373..428773 (+) 1401 WP_014735511.1 Cof-type HAD-IIB family hydrolase -
  FGL16_RS02375 (NCTC10237_00448) - 428775..429146 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  FGL16_RS02380 (NCTC10237_00449) cysK 429172..430098 (-) 927 WP_012774985.1 cysteine synthase A -
  FGL16_RS02385 (NCTC10237_00450) - 430189..430821 (-) 633 WP_014735512.1 YigZ family protein -
  FGL16_RS02390 (NCTC10237_00451) comFA/cflA 430878..432170 (+) 1293 WP_014735513.1 DEAD/DEAH box helicase Machinery gene
  FGL16_RS02395 - 432163..432828 (+) 666 Protein_396 ComF family protein -
  FGL16_RS02400 (NCTC10237_00454) raiA 432905..433447 (+) 543 WP_014735514.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48926.56 Da        Isoelectric Point: 9.1823

>NTDB_id=1127622 FGL16_RS02390 WP_014735513.1 430878..432170(+) (comFA/cflA) [Streptococcus suis strain NCTC10237]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKNF
PITKCLKWKGQLTDWQQRISDGLVANVENNRVTLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSCFPLLIVVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAVAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=1127622 FGL16_RS02390 WP_014735513.1 430878..432170(+) (comFA/cflA) [Streptococcus suis strain NCTC10237]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTTTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAAATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGTGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCTGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGTAAATTAAGTCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTTCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGTGCTTTCCCTTACTCATTGTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGAGTCGGAAGGAGTATGGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAGTCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(295-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae Rx1

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae D39

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae R6

65.893

100

0.66
  comFA/cflA Streptococcus pneumoniae TIGR4

65.893

100

0.66
  comFA/cflA Streptococcus mitis SK321

65.197

100

0.653
  comFA Lactococcus lactis subsp. cremoris KW2

53.401

92.326

0.493
  comFA Latilactobacillus sakei subsp. sakei 23K

37.471

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.349

96.512

0.36

Multiple sequence alignment