Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FGL06_RS02280 Genome accession   NZ_LR594042
Coordinates   435801..437099 (+) Length   432 a.a.
NCBI ID   WP_126437633.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 430801..442099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS02255 (NCTC8133_00452) - 431495..432139 (+) 645 WP_024344653.1 response regulator transcription factor -
  FGL06_RS02260 (NCTC8133_00453) - 432263..433663 (+) 1401 WP_029876003.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGL06_RS02265 (NCTC8133_00454) - 433663..434019 (+) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -
  FGL06_RS02270 (NCTC8133_00455) cysK 434093..435022 (-) 930 WP_021141798.1 cysteine synthase A -
  FGL06_RS02275 (NCTC8133_00456) - 435120..435746 (-) 627 WP_126437632.1 YigZ family protein -
  FGL06_RS02280 (NCTC8133_00457) comFA/cflA 435801..437099 (+) 1299 WP_126437633.1 DEAD/DEAH box helicase Machinery gene
  FGL06_RS02285 (NCTC8133_00458) - 437099..437764 (+) 666 WP_126437634.1 ComF family protein -
  FGL06_RS02290 (NCTC8133_00459) hpf 437841..438389 (+) 549 WP_024344660.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49222.36 Da        Isoelectric Point: 9.4749

>NTDB_id=1127563 FGL06_RS02280 WP_126437633.1 435801..437099(+) (comFA/cflA) [Streptococcus equinus strain NCTC8133]
MEDKNDYYGRIFVESQLSDELKEEAEKLPSMVKRKDNFTCNRCGSIILPDNILQTGQTYCRECLVFGRNISDSYLYYFQQ
KSFQKNNSLNWQGQLTLYQNEVSEGMLSGIAEKKDLLVHAVTGAGKTEMIYHSVAKIIDDGGCVCIASPRIDVCLELYKR
MSRDFSCPITLLHGEAEPYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNKMLYYAVNQSLKKDGVKIFLTATST
DELDKKVRKGDLKKLHLARRFHANPLVVPKMLWLSGVLKSMKKGKIPKKLNLLLKNQRKAGYPLLIFFPNIEQGKRFSMV
LQEKFPTEKIGFVSSQSEDRLELVEKFRKNEITILVSTTILERGVTFPCVDVFVVLANHKLYTKSALVQISGRVGRAAER
PTGELLFLHDGATKSMQQAIKEIKEMNKKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1127563 FGL06_RS02280 WP_126437633.1 435801..437099(+) (comFA/cflA) [Streptococcus equinus strain NCTC8133]
ATGGAAGATAAAAATGACTATTATGGAAGAATTTTTGTTGAGTCTCAATTGTCTGATGAGTTAAAAGAAGAAGCTGAAAA
ACTTCCTTCTATGGTAAAAAGAAAAGACAATTTTACGTGTAACCGCTGCGGAAGCATTATTTTACCAGATAATATTTTAC
AAACTGGTCAGACTTACTGCAGAGAATGTCTAGTTTTTGGTCGTAACATCAGTGATTCTTATCTATATTACTTTCAGCAG
AAAAGTTTTCAAAAAAATAATTCTCTAAACTGGCAAGGGCAACTGACACTTTATCAAAATGAAGTGTCAGAAGGTATGTT
GTCAGGAATTGCTGAAAAGAAAGATTTATTAGTTCATGCTGTGACAGGAGCTGGTAAGACAGAGATGATTTATCACTCAG
TAGCAAAAATAATCGATGACGGTGGTTGTGTTTGTATTGCTAGCCCACGAATTGATGTTTGTTTAGAGCTTTATAAACGT
ATGTCTCGTGATTTTTCATGTCCGATTACTTTATTACATGGGGAAGCTGAGCCTTACAAACGAGCACCGCTCATTATTGC
AACAACTCATCAACTTTTAAAATTCTACCAAGCATTTGATTTATTAATTATTGATGAAGTTGATGCCTTTCCATTTGTTG
ACAATAAAATGCTGTATTACGCAGTAAATCAATCTTTAAAAAAAGATGGTGTCAAGATATTTTTAACAGCCACATCGACA
GATGAATTAGATAAAAAAGTTCGAAAAGGCGACTTAAAAAAATTGCATTTAGCCAGACGTTTTCACGCCAATCCTTTGGT
TGTTCCTAAAATGCTCTGGCTTAGTGGGGTATTAAAGTCAATGAAAAAGGGAAAAATACCTAAAAAATTGAACTTGCTGC
TTAAAAATCAAAGAAAAGCAGGATATCCCTTACTAATCTTTTTTCCAAATATAGAGCAGGGAAAAAGATTTTCGATGGTT
CTGCAAGAAAAATTTCCTACTGAGAAGATTGGTTTTGTGTCAAGTCAGAGCGAAGATAGACTTGAATTAGTTGAAAAATT
TAGAAAGAACGAAATAACAATTTTAGTCAGCACAACCATCTTAGAACGTGGGGTCACATTTCCTTGTGTTGACGTATTTG
TTGTATTAGCGAATCACAAATTATACACTAAAAGTGCCTTGGTTCAAATTTCTGGGCGAGTCGGTAGAGCTGCTGAACGA
CCAACAGGAGAATTATTATTTTTGCACGATGGCGCTACAAAATCTATGCAACAAGCGATTAAAGAAATAAAGGAAATGAA
CAAGAAAGGAGGATTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-397)

DEAD/DEAH box helicase (DEAD)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

62.295

98.843

0.616
  comFA/cflA Streptococcus pneumoniae D39

62.295

98.843

0.616
  comFA/cflA Streptococcus pneumoniae R6

62.295

98.843

0.616
  comFA/cflA Streptococcus pneumoniae TIGR4

62.295

98.843

0.616
  comFA/cflA Streptococcus mitis NCTC 12261

60.648

100

0.606
  comFA/cflA Streptococcus mitis SK321

60.417

100

0.604
  comFA Lactococcus lactis subsp. cremoris KW2

50.508

91.204

0.461
  comFA Bacillus subtilis subsp. subtilis str. 168

36.054

100

0.368
  comFA Latilactobacillus sakei subsp. sakei 23K

36.092

100

0.363

Multiple sequence alignment