Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   ACAty_RS13540 Genome accession   NZ_CP005986
Coordinates   2757577..2758944 (+) Length   455 a.a.
NCBI ID   WP_004869549.1    Uniprot ID   A0A059ZYE0
Organism   Acidithiobacillus caldus ATCC 51756     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2752577..2763944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAty_RS13525 (Acaty_c2709) aroE 2753428..2754300 (+) 873 WP_004869542.1 shikimate dehydrogenase -
  ACAty_RS13530 (Acaty_c2710) pilB 2754276..2755982 (+) 1707 WP_004869544.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACAty_RS13535 (Acaty_c2711) - 2756027..2757580 (+) 1554 WP_004869546.1 PAS domain-containing sensor histidine kinase -
  ACAty_RS13540 (Acaty_c2712) pilR 2757577..2758944 (+) 1368 WP_004869549.1 sigma-54 dependent transcriptional regulator Regulator
  ACAty_RS13545 (Acaty_c2713) - 2758934..2759719 (+) 786 WP_004869552.1 A24 family peptidase -
  ACAty_RS13550 (Acaty_c2714) coaE 2759738..2760325 (+) 588 WP_004869555.1 dephospho-CoA kinase -
  ACAty_RS13555 (Acaty_c2715) zapD 2760430..2761182 (+) 753 WP_226823468.1 cell division protein ZapD -
  ACAty_RS13560 (Acaty_c2716) - 2761194..2762201 (+) 1008 WP_004869560.1 class 1 fructose-bisphosphatase -
  ACAty_RS13565 (Acaty_c2717) - 2762284..2763030 (-) 747 WP_004869563.1 complement resistance protein TraT -
  ACAty_RS13570 (Acaty_c2718) - 2763176..2763601 (+) 426 WP_226047576.1 ClpXP protease specificity-enhancing factor -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 49960.73 Da        Isoelectric Point: 6.9080

>NTDB_id=112753 ACAty_RS13540 WP_004869549.1 2757577..2758944(+) (pilR) [Acidithiobacillus caldus ATCC 51756]
MNASVRQRKRALIVDDEPTIVELLGITLEGMGVEVLACHSLAEAFAALGKGPPSLCLTDLRLGDGSGMQLLHKVRELYPQ
VPVAVITAYASAEGAVEAMRAGAFDFMTKPIELARLRRLVSEAIALGELPRESVDLSERLVGESPGMVALRERVRLLGRS
NAPVHIRGESGTGKELVARAIHDASPRREKAFIAVNCGAIPENLMESEFFGAEKGAYSGAVQRREGLFVAANGGTLFLDE
IAELPLTTQVKLLRVLQERVVRPLGGLREQSIDIRLICATHRDLRRMVEEGTFREDLFYRINVVPIEIPPLRERREDIPL
LAQTLLQRLCQRHGRPPANLAPAALAWLSNRDFPGNVRELENLLERALALQSQPLLHREDLEPTAELAVARAPLPAAAPA
ADTALTKRLAEAEWRYLADLQIRLGDRPEEMAKALGISLQSLHLRLARGGSNRDS

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=112753 ACAty_RS13540 WP_004869549.1 2757577..2758944(+) (pilR) [Acidithiobacillus caldus ATCC 51756]
GTGAATGCCAGTGTTCGGCAAAGGAAACGGGCGCTCATCGTCGACGATGAGCCCACCATCGTGGAACTGCTGGGTATCAC
CTTGGAAGGCATGGGGGTCGAGGTCTTGGCTTGCCATAGCCTGGCCGAAGCCTTTGCCGCCCTGGGCAAGGGCCCACCAT
CGCTGTGCCTGACGGATCTGCGCCTGGGCGACGGCTCGGGCATGCAACTCCTGCACAAGGTCCGCGAACTCTACCCGCAG
GTGCCGGTGGCGGTGATCACCGCCTACGCCTCGGCGGAGGGCGCGGTGGAAGCCATGCGCGCCGGCGCCTTCGACTTCAT
GACCAAGCCCATAGAACTGGCACGTCTGCGCCGCCTGGTGAGCGAGGCCATCGCCCTTGGGGAGTTGCCCCGGGAGAGCG
TAGATCTCAGCGAGCGCCTGGTGGGCGAAAGCCCCGGCATGGTGGCCCTGCGCGAGCGCGTTCGCCTGCTGGGACGCAGC
AATGCACCGGTGCATATTCGCGGTGAATCGGGCACCGGCAAGGAACTGGTGGCCCGCGCCATACACGATGCAAGCCCACG
TCGGGAAAAGGCATTCATTGCCGTCAACTGCGGCGCCATCCCGGAAAATCTCATGGAGAGCGAGTTTTTTGGTGCCGAAA
AAGGTGCCTATTCCGGCGCCGTGCAACGGCGGGAAGGACTCTTCGTGGCAGCCAATGGTGGCACGCTCTTTCTCGACGAA
ATAGCCGAACTGCCGCTGACCACGCAGGTGAAACTGCTGCGGGTGCTGCAAGAGCGGGTGGTGCGACCGCTGGGTGGCCT
GCGCGAGCAGAGTATCGATATCCGCCTGATCTGTGCCACCCACCGCGATCTGCGCCGGATGGTGGAGGAGGGCACTTTTC
GCGAAGACCTCTTCTACCGCATCAATGTCGTACCCATAGAGATTCCGCCCCTGCGCGAACGCCGCGAGGACATCCCGCTA
CTGGCGCAAACGCTACTGCAGCGCCTCTGCCAGCGGCACGGACGTCCCCCGGCGAACCTCGCCCCCGCTGCGCTGGCCTG
GCTGTCCAACCGCGATTTCCCGGGCAACGTACGTGAGTTGGAGAACCTCCTGGAGCGGGCGCTCGCCCTACAGTCACAGC
CACTGCTGCACCGGGAAGATCTGGAGCCCACGGCGGAGCTCGCGGTGGCGCGGGCGCCACTGCCCGCTGCCGCACCCGCC
GCGGACACGGCCCTCACCAAGCGCCTGGCCGAGGCAGAGTGGCGCTATCTGGCCGACCTGCAGATCCGCCTTGGCGATCG
ACCCGAGGAAATGGCAAAGGCCCTGGGCATAAGCCTACAATCGCTCCATCTGCGTCTCGCCCGGGGAGGATCGAATCGTG
ATTCCTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(12-119)

Sigma-54 interaction domain (Sigma54_activat)

(140-307)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A059ZYE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

49.224

99.121

0.488
  pilR Acinetobacter baumannii strain A118

40.773

100

0.418

Multiple sequence alignment