Detailed information NTG1127488

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FGL12_RS03825
• Genome accession: NZ_LR594041
• Coordinates: 795960..796964 (+)
• Length: 334 a.a.
• NCBI ID: WP_012000235.1
• Uniprot ID: Q3Y532
• Organism: Streptococcus gordonii strain NCTC9124
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 790960..801964

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL12_RS03800 (NCTC9124_00763)	-	791286..792314 (-)	1029	WP_041789612.1	ABC transporter substrate-binding protein	-
FGL12_RS03805 (NCTC9124_00764)	-	792459..793214 (-)	756	WP_012000231.1	ABC transporter ATP-binding protein	-
FGL12_RS03810 (NCTC9124_00765)	-	793216..794262 (-)	1047	WP_012000232.1	iron ABC transporter permease	-
FGL12_RS10990	-	794555..794662 (+)	108	Protein_732	DNA-entry nuclease	-
FGL12_RS03820 (NCTC9124_00766)	-	794713..795795 (-)	1083	WP_012000233.1	Xaa-Pro peptidase family protein	-
FGL12_RS03825 (NCTC9124_00767)	ccpA	795960..796964 (+)	1005	WP_012000235.1	catabolite control protein A	Regulator
FGL12_RS03830 (NCTC9124_00768)	-	797109..798107 (+)	999	WP_041789613.1	glycosyltransferase	-
FGL12_RS03835 (NCTC9124_00769)	-	798109..799422 (+)	1314	WP_012000237.1	glycosyltransferase family 4 protein	-
FGL12_RS03840 (NCTC9124_00770)	-	799458..799820 (+)	363	WP_012000238.1	hypothetical protein	-
FGL12_RS10995 (NCTC9124_00772)	-	800154..800525 (+)	372	WP_012000239.1	hypothetical protein	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 37022.13 Da
• Isoelectric Point: 6.5109

>NTDB_id=1127488 FGL12_RS03825 WP_012000235.1 795960..796964(+) (ccpA) [Streptococcus gordonii strain NCTC9124]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPSITNSYFS
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTIDVEHQLPS
VNIDYKQATIDAITFLAKRNKKIAFVCGPLVDDINGKVRLSGYKTALKSKKLSYSEGLVFESKYGYDDGYNLAERVIASK
ATAAFVTGDELAAGLLNGLADCGVKIPEDFEIITSDDSQISRYTRPNLSTISQPLYDLGAISMRMLTKIMHKEELEEREV
VLSHGIYERNSTRK

Nucleotide

• Length: 1005 bp

>NTDB_id=1127488 FGL12_RS03825 WP_012000235.1 795960..796964(+) (ccpA) [Streptococcus gordonii strain NCTC9124]
ATGAACACAGACGATACAGTAACCATTTATGATGTCGCCCGTGAAGCAGGGGTTTCTATGGCGACAGTTAGTCGTGTAGT
TAATGGAAACAAGAATGTAAAAGAAAACACTCGGAAAAAAGTTTTGGAAGTAATTGATCGCCTTGATTATCGTCCAAATG
CAGTAGCTCGTGGTTTGGCTAGCAAGAAGACTACGACAGTTGGTGTTGTGATTCCAAGTATTACAAATAGTTATTTCTCA
ACACTCGCCAAGGGAATTGATGATATTGCTGAGATGTATAAATACAATATCGTCCTAGCAAACAGCGATGAGGATGATGA
TAAGGAAGTTTCAGTTGTAAACACTCTCTTTTCGAAACAAGTAGATGGTATTATCTTTATGGGTTACCACCTTACTGAAA
AGATTCGGTCAGAATTTTCACGCTCACGCACGCCAGTTGTCTTGGCTGGAACTATTGATGTGGAGCACCAATTGCCAAGT
GTTAATATAGATTATAAACAGGCTACAATTGATGCTATCACATTCCTTGCTAAGCGCAATAAAAAAATTGCTTTTGTGTG
CGGACCTTTAGTTGATGATATCAATGGAAAAGTACGCTTATCCGGTTATAAAACGGCTCTTAAGAGCAAAAAGCTGTCAT
ACAGCGAAGGTCTTGTTTTTGAGTCTAAGTATGGCTATGATGATGGCTATAATTTAGCTGAACGAGTAATTGCTTCTAAA
GCAACGGCTGCTTTTGTTACAGGTGATGAGCTGGCAGCTGGTCTTTTAAACGGACTAGCTGATTGCGGAGTAAAAATTCC
AGAGGATTTTGAAATTATTACTAGCGATGATTCACAAATATCTCGCTATACACGTCCAAATTTGTCGACTATAAGCCAGC
CTTTATATGATTTAGGTGCTATTAGTATGCGTATGCTGACTAAAATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
GTTCTATCTCATGGTATTTACGAACGGAACTCAACTAGAAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (175-332)

3D structure

• AlphaFold DB: Q3Y532

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	100	100	1
ccpA	Streptococcus pneumoniae D39	86.826	100	0.868
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.798	99.102	0.563