Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FGL00_RS05435 Genome accession   NZ_LR594034
Coordinates   1074649..1075959 (-) Length   436 a.a.
NCBI ID   WP_138083874.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1069649..1080959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL00_RS05405 (NCTC8546_01118) - 1070084..1070473 (-) 390 WP_003058840.1 cytidine deaminase -
  FGL00_RS05410 (NCTC8546_01119) deoC 1070460..1071122 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  FGL00_RS05415 (NCTC8546_01120) - 1071138..1072415 (-) 1278 WP_015017041.1 pyrimidine-nucleoside phosphorylase -
  FGL00_RS05420 (NCTC8546_01121) - 1072402..1073001 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  FGL00_RS05425 (NCTC8546_01122) coaA 1073269..1074189 (+) 921 WP_048327791.1 type I pantothenate kinase -
  FGL00_RS05430 (NCTC8546_01123) rpsT 1074243..1074491 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  FGL00_RS05435 (NCTC8546_01124) ciaH 1074649..1075959 (-) 1311 WP_138083874.1 HAMP domain-containing sensor histidine kinase Regulator
  FGL00_RS05440 (NCTC8546_01125) ciaR 1075952..1076626 (-) 675 WP_003060678.1 response regulator transcription factor Regulator
  FGL00_RS05445 (NCTC8546_01126) - 1076830..1079367 (-) 2538 WP_138083875.1 M1 family metallopeptidase -
  FGL00_RS05450 (NCTC8546_01127) phoU 1079568..1080221 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49964.56 Da        Isoelectric Point: 8.2375

>NTDB_id=1127247 FGL00_RS05435 WP_138083874.1 1074649..1075959(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNFFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1127247 FGL00_RS05435 WP_138083874.1 1074649..1075959(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTTTTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATCAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.142

100

0.514
  ciaH Streptococcus pneumoniae D39

51.142

100

0.514
  ciaH Streptococcus pneumoniae R6

51.142

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.142

100

0.514

Multiple sequence alignment