Detailed information NTG1127180

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: FGK99_RS05045
• Genome accession: NZ_LR594033
• Coordinates: 1061160..1061897 (+)
• Length: 245 a.a.
• NCBI ID: WP_043052135.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC4675
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1056160..1066897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK99_RS05015 (NCTC4675_01015)	-	1056602..1057507 (-)	906	WP_012677986.1	diacylglycerol/lipid kinase family protein	-
FGK99_RS05020 (NCTC4675_01016)	trhA	1057617..1058267 (-)	651	WP_043030784.1	PAQR family membrane homeostasis protein TrhA	-
FGK99_RS05025 (NCTC4675_01017)	-	1058251..1058706 (-)	456	WP_138119294.1	DUF1836 domain-containing protein	-
FGK99_RS05030 (NCTC4675_01018)	-	1058966..1059721 (+)	756	WP_138119296.1	class I SAM-dependent methyltransferase	-
FGK99_RS05035 (NCTC4675_01019)	-	1059749..1060087 (+)	339	WP_138119298.1	cupin domain-containing protein	-
FGK99_RS05040 (NCTC4675_01020)	-	1060089..1060394 (+)	306	WP_043052134.1	AraC family ligand binding domain-containing protein	-
FGK99_RS05045 (NCTC4675_01021)	comE/blpR	1061160..1061897 (+)	738	WP_043052135.1	response regulator transcription factor	Regulator
FGK99_RS05050 (NCTC4675_01022)	-	1062270..1062500 (+)	231	WP_021320759.1	Blp family class II bacteriocin	-
FGK99_RS05060 (NCTC4675_01023)	-	1063293..1064141 (+)	849	WP_138119300.1	thioredoxin domain-containing protein	-
FGK99_RS05065 (NCTC4675_01024)	-	1064621..1064902 (+)	282	WP_012515598.1	lactococcin 972 family bacteriocin	-
FGK99_RS05070 (NCTC4675_01025)	-	1065007..1065714 (+)	708	Protein_978	bacteriocin-associated integral membrane family protein	-
FGK99_RS05075 (NCTC4675_01026)	tnpA	1065840..1066313 (+)	474	WP_043026004.1	IS200/IS605 family transposase	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28920.36 Da
• Isoelectric Point: 7.8796

>NTDB_id=1127180 FGK99_RS05045 WP_043052135.1 1061160..1061897(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=1127180 FGK99_RS05045 WP_043052135.1 1061160..1061897(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATATTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	37.295	99.592	0.371