Detailed information NTG1127039

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FGK91_RS02390
• Genome accession: NZ_LR590483
• Coordinates: 427447..428448 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8318
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 422447..433448

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK91_RS02365 (NCTC8318_00467)	-	423121..423804 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
FGK91_RS02370 (NCTC8318_00468)	-	424015..424941 (-)	927	WP_023078729.1	glycosyltransferase family 2 protein	-
FGK91_RS02375 (NCTC8318_00469)	-	425086..425463 (-)	378	WP_002985686.1	VOC family protein	-
FGK91_RS02380 (NCTC8318_00470)	-	425474..426139 (-)	666	WP_023078767.1	NAD(P)H-dependent oxidoreductase	-
FGK91_RS02385 (NCTC8318_00471)	-	426188..427273 (-)	1086	WP_023078753.1	Xaa-Pro peptidase family protein	-
FGK91_RS02390 (NCTC8318_00472)	ccpA	427447..428448 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
FGK91_RS02395 (NCTC8318_00473)	-	428579..429577 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
FGK91_RS02400 (NCTC8318_00474)	-	429579..430913 (+)	1335	WP_023078780.1	glycosyltransferase family 4 protein	-
FGK91_RS02405 (NCTC8318_00476)	thrS	431335..433278 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1127039 FGK91_RS02390 WP_002985680.1 427447..428448(+) (ccpA) [Streptococcus pyogenes strain NCTC8318]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1127039 FGK91_RS02390 WP_002985680.1 427447..428448(+) (ccpA) [Streptococcus pyogenes strain NCTC8318]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559