Detailed information NTG1126948

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: FGL10_RS10000
• Genome accession: NZ_LR590477
• Coordinates: 1846441..1846890 (+)
• Length: 149 a.a.
• NCBI ID: WP_003710616.1
• Uniprot ID: A0A378VPN9
• Organism: Neisseria lactamica strain NCTC10617
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1841441..1851890

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL10_RS12675	-	1845887..1846353 (+)	467	Protein_1756	helix-hairpin-helix domain-containing protein	-
FGL10_RS10000 (NCTC10617_01750)	comP	1846441..1846890 (+)	450	WP_003710616.1	type IV pilin protein	Machinery gene
FGL10_RS10005	-	1846897..1847265 (-)	369	WP_003710619.1	5'-nucleotidase	-
FGL10_RS10010 (NCTC10617_01752)	-	1847785..1848129 (+)	345	WP_003710626.1	hypothetical protein	-
FGL10_RS10015 (NCTC10617_01753)	-	1848275..1848715 (+)	441	WP_003710628.1	hypothetical protein	-
FGL10_RS10020 (NCTC10617_01754)	-	1848801..1849012 (-)	212	Protein_1761	succinyldiaminopimelate transaminase	-

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16836.73 Da
• Isoelectric Point: 9.6170

>NTDB_id=1126948 FGL10_RS10000 WP_003710616.1 1846441..1846890(+) (comP) [Neisseria lactamica strain NCTC10617]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENSVTFICKKSASSCDDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=1126948 FGL10_RS10000 WP_003710616.1 1846441..1846890(+) (comP) [Neisseria lactamica strain NCTC10617]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCGGCTTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGGTTTAAACAAACATCTACTAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATTGCGCGTGGGGCTTTAGATAGTAAGTTCATGTTAAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAGAATTCGGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGCGATGACG
GACTAGATTATTTTAAAGGTAACGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

3D structure

• AlphaFold DB: A0A378VPN9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	98.658	100	0.987
comP	Neisseria meningitidis 8013	97.987	100	0.98
comP	Neisseria subflava NJ9703	48.98	98.658	0.483