Detailed information NTG1126938

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FGL10_RS07145
• Genome accession: NZ_LR590477
• Coordinates: 1360877..1361737 (+)
• Length: 286 a.a.
• NCBI ID: WP_003710975.1
• Uniprot ID: A0A1V0DRE8
• Organism: Neisseria lactamica strain NCTC10617
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1355877..1366737

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL10_RS07125 (NCTC10617_01238)	dapD	1356543..1357364 (-)	822	WP_003710970.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
FGL10_RS07130	-	1357374..1357604 (-)	231	WP_036475185.1	hypothetical protein	-
FGL10_RS07135 (NCTC10617_01239)	pgi	1357574..1359217 (-)	1644	WP_036475187.1	glucose-6-phosphate isomerase	-
FGL10_RS07140 (NCTC10617_01240)	pilG	1359571..1360803 (+)	1233	WP_003710974.1	type 4 pilus assembly protein PilG	Machinery gene
FGL10_RS07145 (NCTC10617_01241)	pilD	1360877..1361737 (+)	861	WP_003710975.1	prepilin peptidase	Machinery gene
FGL10_RS07150 (NCTC10617_01242)	coaE	1361739..1362371 (+)	633	WP_003710976.1	dephospho-CoA kinase	-
FGL10_RS07155 (NCTC10617_01243)	-	1362364..1362573 (+)	210	WP_003710977.1	DNA gyrase inhibitor YacG	-
FGL10_RS07160 (NCTC10617_01244)	pilF	1362658..1364334 (-)	1677	WP_003710978.1	type IV-A pilus assembly ATPase PilB	Machinery gene
FGL10_RS07175 (NCTC10617_01246)	-	1364966..1365412 (-)	447	WP_003710982.1	DUF441 domain-containing protein	-
FGL10_RS07180 (NCTC10617_01247)	-	1365417..1366391 (-)	975	WP_003710984.1	polyprenyl synthetase family protein	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31231.27 Da
• Isoelectric Point: 8.7141

>NTDB_id=1126938 FGL10_RS07145 WP_003710975.1 1360877..1361737(+) (pilD) [Neisseria lactamica strain NCTC10617]
MFALSVLPPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPSIELLTGVLFGLVAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=1126938 FGL10_RS07145 WP_003710975.1 1360877..1361737(+) (pilD) [Neisseria lactamica strain NCTC10617]
ATGTTTGCTTTATCTGTACTGCCTCCGTTTGCCGTACCTTTGGCAGCGGTGTTGGGACTGCTGGTCGGCAGTTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTGATGATGGAGCGCGGTTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGATGAGGAAAGCCGCACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCGAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTACCC
CTCTATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCATTATGGCTCTTATGTGCGGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCAGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: A0A1V0DRE8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	97.193	99.65	0.969
pilD	Acinetobacter baumannii D1279779	48.485	92.308	0.448
pilD	Acinetobacter nosocomialis M2	48.485	92.308	0.448
pilD	Vibrio campbellii strain DS40M4	44.251	100	0.444
pilD	Vibrio cholerae strain A1552	46.014	96.503	0.444