Detailed information NTG1126855

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: FGK94_RS01475
• Genome accession: NZ_LR590471
• Coordinates: 326156..326893 (-)
• Length: 245 a.a.
• NCBI ID: WP_138082835.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11854
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 321156..331893

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK94_RS01440 (NCTC11854_00305)	-	321849..322130 (-)	282	WP_080332480.1	lactococcin 972 family bacteriocin	-
FGK94_RS01455 (NCTC11854_00307)	-	323001..323231 (-)	231	WP_012515596.1	Blp family class II bacteriocin	-
FGK94_RS01460 (NCTC11854_00308)	-	323493..324656 (-)	1164	WP_043029698.1	ABC transporter permease subunit	-
FGK94_RS01465 (NCTC11854_00309)	-	324662..325516 (-)	855	WP_043029697.1	ABC transporter ATP-binding protein	-
FGK94_RS01470 (NCTC11854_00310)	-	325583..325783 (-)	201	WP_043029696.1	hypothetical protein	-
FGK94_RS01475 (NCTC11854_00311)	comE/blpR	326156..326893 (-)	738	WP_138082835.1	response regulator transcription factor	Regulator
FGK94_RS01480 (NCTC11854_00312)	-	327656..327961 (-)	306	WP_012515590.1	hypothetical protein	-
FGK94_RS01485 (NCTC11854_00313)	-	327963..328301 (-)	339	WP_138082837.1	cupin domain-containing protein	-
FGK94_RS01490 (NCTC11854_00314)	-	328329..329084 (-)	756	WP_138082839.1	class I SAM-dependent methyltransferase	-
FGK94_RS01495 (NCTC11854_00315)	-	329345..329800 (+)	456	WP_043025808.1	DUF1836 domain-containing protein	-
FGK94_RS01500 (NCTC11854_00316)	trhA	329784..330434 (+)	651	WP_043030784.1	PAQR family membrane homeostasis protein TrhA	-
FGK94_RS01505 (NCTC11854_00317)	-	330544..331449 (+)	906	WP_138082841.1	diacylglycerol/lipid kinase family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28884.16 Da
• Isoelectric Point: 7.5378

>NTDB_id=1126855 FGK94_RS01475 WP_138082835.1 326156..326893(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIRYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFENGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=1126855 FGK94_RS01475 WP_138082835.1 326156..326893(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAGCAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCGGTTGCTCGTGAGATTAGAAAGCGTGAC
CCTTATGCTCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTATCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTAGGTATGCTTATGAAGAACAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGCAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTT
ATTGAGACCTCTAGTACCCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCGAGAATGGGCAGTCTTGCATGGTTTCAAGATTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.719	98.776	0.531
comE/comE1	Streptococcus equinus JB1	45.868	98.776	0.453
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367