Detailed information NTG1126792

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FGK81_RS07280
• Genome accession: NZ_LR590466
• Coordinates: 1430265..1431266 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8193
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1425265..1436266

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK81_RS07265 (NCTC8193_01448)	thrS	1425435..1427378 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
FGK81_RS07270 (NCTC8193_01450)	-	1427800..1429134 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
FGK81_RS07275 (NCTC8193_01451)	-	1429136..1430134 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
FGK81_RS07280 (NCTC8193_01452)	ccpA	1430265..1431266 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
FGK81_RS07285 (NCTC8193_01453)	-	1431440..1432525 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
FGK81_RS07290 (NCTC8193_01454)	-	1432574..1433239 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
FGK81_RS07295 (NCTC8193_01455)	-	1433250..1433627 (+)	378	WP_002985686.1	VOC family protein	-
FGK81_RS07300 (NCTC8193_01456)	-	1433772..1434698 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
FGK81_RS07305 (NCTC8193_01457)	-	1434909..1435592 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1126792 FGK81_RS07280 WP_002985680.1 1430265..1431266(-) (ccpA) [Streptococcus pyogenes strain NCTC8193]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1126792 FGK81_RS07280 WP_002985680.1 1430265..1431266(-) (ccpA) [Streptococcus pyogenes strain NCTC8193]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGCAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559