Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FGK83_RS00180 Genome accession   NZ_LR590465
Coordinates   38899..39573 (-) Length   224 a.a.
NCBI ID   WP_112102720.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC8468     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 33899..44573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK83_RS00160 (NCTC8468_00030) - 35606..35956 (+) 351 WP_005686227.1 HIT domain-containing protein -
  FGK83_RS00165 (NCTC8468_00031) - 35956..36306 (+) 351 WP_114892869.1 YcfL family protein -
  FGK83_RS00170 (NCTC8468_00032) nagZ 36310..37362 (+) 1053 WP_114892870.1 beta-N-acetylhexosaminidase -
  FGK83_RS00175 (NCTC8468_00033) rlmC 37359..38546 (+) 1188 WP_138171378.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  FGK83_RS00180 (NCTC8468_00034) crp 38899..39573 (-) 675 WP_112102720.1 cAMP-activated global transcriptional regulator CRP Regulator
  FGK83_RS00185 (NCTC8468_00035) - 39558..39809 (-) 252 WP_032824522.1 YheU family protein -
  FGK83_RS00190 (NCTC8468_00036) slmA 39832..40488 (-) 657 WP_118802508.1 nucleoid occlusion factor SlmA -
  FGK83_RS00195 (NCTC8468_00037) dut 40492..40947 (-) 456 WP_138171379.1 dUTP diphosphatase -
  FGK83_RS00200 (NCTC8468_00038) coaBC 41535..42749 (-) 1215 WP_138171380.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  FGK83_RS00205 (NCTC8468_00039) radC 42912..43577 (+) 666 WP_050846688.1 RadC family protein -
  FGK83_RS00210 (NCTC8468_00040) rpmB 43790..44026 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  FGK83_RS00215 (NCTC8468_00041) rpmG 44038..44208 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25104.79 Da        Isoelectric Point: 6.6042

>NTDB_id=1126727 FGK83_RS00180 WP_112102720.1 38899..39573(-) (crp) [Haemophilus influenzae strain NCTC8468]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEVGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1126727 FGK83_RS00180 WP_112102720.1 38899..39573(-) (crp) [Haemophilus influenzae strain NCTC8468]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGTGGGATTATTTGATGAGGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTAATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.536

100

0.955
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment