Detailed information NTG1126600

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: E0F34_RS11060
• Genome accession: NZ_LR536843
• Coordinates: 2048129..2049427 (-)
• Length: 432 a.a.
• NCBI ID: WP_130885257.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2043129..2054427

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS11040 (SAMEA104035599_02104)	rplI	2044284..2044736 (-)	453	WP_000864220.1	50S ribosomal protein L9	-
E0F34_RS11045 (SAMEA104035599_02105)	-	2044733..2046706 (-)	1974	WP_000715109.1	DHH family phosphoesterase	-
E0F34_RS11050 (SAMEA104035599_02106)	hpf	2046842..2047390 (-)	549	WP_000599107.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
E0F34_RS11055 (SAMEA104035599_02107)	comFC/cflB	2047470..2048132 (-)	663	WP_061649835.1	ComF family protein	Machinery gene
E0F34_RS11060 (SAMEA104035599_02108)	comFA/cflA	2048129..2049427 (-)	1299	WP_130885257.1	DEAD/DEAH box helicase	Machinery gene
E0F34_RS11065 (SAMEA104035599_02109)	-	2049483..2050118 (+)	636	WP_000395738.1	YigZ family protein	-
E0F34_RS11070 (SAMEA104035599_02110)	cysK	2050403..2051329 (+)	927	WP_130885258.1	cysteine synthase A	-
E0F34_RS11075 (SAMEA104035599_02111)	tsf	2051450..2052490 (-)	1041	WP_000808062.1	translation elongation factor Ts	-
E0F34_RS11080 (SAMEA104035599_02112)	rpsB	2052569..2053348 (-)	780	WP_000268466.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 49537.55 Da
• Isoelectric Point: 8.5992

>NTDB_id=1126600 E0F34_RS11060 WP_130885257.1 2048129..2049427(-) (comFA/cflA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MKVNLDYLGRLFTESELTEEERQLAEKLPAMRKEKGKLFCQRCNSIILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPMLYHAVKNSVKENGLRIFLTATST
NELDKKVRLGELKRLNLPRRFHGNSLIIPKPIWLSDFNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEI
LQEQFPNEKIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL

Nucleotide

• Length: 1299 bp

>NTDB_id=1126600 E0F34_RS11060 WP_130885257.1 2048129..2049427(-) (comFA/cflA) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGAAAGTAAATTTAGATTATCTCGGTCGTTTATTTACTGAGAGTGAATTAACAGAAGAAGAACGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAGGGGAAACTTTTCTGTCAACGCTGTAATAGTATTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGAGAGTGCTTGCTGATGAAGCGAGTCAGAAGTGATCAAACTTTATACTATTTTCCGCAG
GAGGATTTTCCGAAGCAAGATGTTCTCAAATGGCGCGGCCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGCT
TCAAGCAGTAGACAAGCAAAAGCCAACCTTAGTTCATGCGGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTAG
TGGCTAAAGTGATCAATGCGGGTGGTGCAGTGTGTTTGGCTAGTCCTCGCATAGATGTTTGTTTGGAGCTGTACAAGCGC
CTGCAACAGGATTTTTCTTGCGGAATAGCTTTGCTACATGGAGAATCGGAACCTTATTTTCGAACACCACTAGTTGTTGC
AACAACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCTTTTCCTTATGTTG
ATAATCCCATGCTTTACCACGCTGTCAAGAATAGTGTAAAGGAGAATGGATTGAGAATCTTTTTAACAGCGACTTCGACC
AATGAGTTAGATAAAAAGGTCCGTTTAGGAGAACTAAAAAGACTGAATTTACCGAGACGGTTTCATGGAAATTCGTTGAT
TATTCCAAAACCAATTTGGTTATCGGATTTTAATCGCTACTTAGACAAGAATCGTTTGTCACCAAAGTTAAAGTCCTATA
TTGAGAAGCAGAGAAAGACAGCTTATCCGTTACTCATTTTTGCTTCAGAAATTAAGAAAGGGGAGCAGTTAGCAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAGCAAGTACAAGCTTT
TCGAGATGGAGAACTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAGGCCAATCATCGTTTGTTTACCAAGTCTAGTTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGATGGGTTAAATGCTTCAATCAAGAAGGCGATTAAGGAAATTCAGATGATGAA
TAAGGAGGCTGGTCTATGA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (293-396)

• Type III restriction enzyme, res subunit (ResIII) (94-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus pneumoniae Rx1	99.306	100	0.993
comFA/cflA	Streptococcus pneumoniae D39	99.306	100	0.993
comFA/cflA	Streptococcus pneumoniae R6	99.306	100	0.993
comFA/cflA	Streptococcus pneumoniae TIGR4	99.074	100	0.991
comFA/cflA	Streptococcus mitis NCTC 12261	92.824	100	0.928
comFA/cflA	Streptococcus mitis SK321	91.898	100	0.919
comFA	Lactococcus lactis subsp. cremoris KW2	52.451	94.444	0.495
comFA	Latilactobacillus sakei subsp. sakei 23K	38.979	99.769	0.389