Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   E0F34_RS09285 Genome accession   NZ_LR536843
Coordinates   1716824..1717633 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1711824..1722633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F34_RS09270 (SAMEA104035599_01765) - 1714289..1716160 (-) 1872 WP_000150986.1 Eco57I restriction-modification methylase domain-containing protein -
  E0F34_RS09275 (SAMEA104035599_01766) - 1716235..1716489 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE family toxin -
  E0F34_RS09280 (SAMEA104035599_01767) relB 1716491..1716733 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  E0F34_RS09285 (SAMEA104035599_01768) vicX 1716824..1717633 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  E0F34_RS09290 (SAMEA104035599_01769) micB 1717635..1718984 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E0F34_RS09295 (SAMEA104035599_01770) micA 1718977..1719681 (-) 705 WP_000722076.1 response regulator YycF Regulator
  E0F34_RS09300 (SAMEA104035599_01771) mutY 1719736..1720911 (-) 1176 WP_050202456.1 A/G-specific adenine glycosylase -
  E0F34_RS12185 - 1721008..1721133 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=1126572 E0F34_RS09285 WP_001289493.1 1716824..1717633(-) (vicX) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1126572 E0F34_RS09285 WP_001289493.1 1716824..1717633(-) (vicX) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTGGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGCAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACTTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGACAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment