Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   E0F40_RS09545 Genome accession   NZ_LR216065
Coordinates   1775641..1776261 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770641..1781261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F40_RS09520 (SAMEA3714487_01804) recA 1771016..1772182 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  E0F40_RS09525 (SAMEA3714487_01805) cinA 1772237..1773493 (-) 1257 WP_000642683.1 competence/damage-inducible protein A Machinery gene
  E0F40_RS09530 (SAMEA3714487_01806) brpA 1773580..1774596 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  E0F40_RS09535 (SAMEA3714487_01807) - 1774604..1775122 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  E0F40_RS09540 (SAMEA3714487_01808) tsaE 1775112..1775555 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  E0F40_RS09545 (SAMEA3714487_01809) comM 1775641..1776261 (-) 621 WP_000839908.1 hypothetical protein Regulator
  E0F40_RS09555 (SAMEA3714487_01810) - 1776644..1777507 (-) 864 WP_001093619.1 helix-turn-helix domain-containing protein -
  E0F40_RS11795 (SAMEA3714487_01811) - 1777696..1777866 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  E0F40_RS09565 (SAMEA3714487_01812) - 1778316..1780331 (+) 2016 WP_000732374.1 DUF1430 domain-containing protein -
  E0F40_RS09570 (SAMEA3714487_01813) - 1780333..1780965 (+) 633 WP_000571422.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=1126363 E0F40_RS09545 WP_000839908.1 1775641..1776261(-) (comM) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1126363 E0F40_RS09545 WP_000839908.1 1775641..1776261(-) (comM) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment