Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   E0F31_RS09775 Genome accession   NZ_LR216064
Coordinates   1819598..1820608 (-) Length   336 a.a.
NCBI ID   WP_000990607.1    Uniprot ID   A0A0B7LZL8
Organism   Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6     
Function   regulate comCDE transcription and transformation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1814598..1825608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F31_RS09750 (SAMEA3714520_01836) - 1815763..1816057 (-) 295 Protein_1846 hypothetical protein -
  E0F31_RS09755 (SAMEA3714520_01837) - 1816219..1816671 (+) 453 WP_000079148.1 universal stress protein -
  E0F31_RS09760 (SAMEA3714520_01838) - 1816706..1818094 (-) 1389 WP_050168301.1 Cof-type HAD-IIB family hydrolase -
  E0F31_RS09765 (SAMEA3714520_01839) - 1818160..1819122 (+) 963 WP_001124777.1 asparaginase -
  E0F31_RS09770 (SAMEA3714520_01840) - 1819151..1819534 (-) 384 WP_061630317.1 hypothetical protein -
  E0F31_RS09775 (SAMEA3714520_01841) ccpA 1819598..1820608 (-) 1011 WP_000990607.1 catabolite control protein A Regulator
  E0F31_RS09780 (SAMEA3714520_01842) - 1821033..1821632 (-) 600 WP_000866703.1 response regulator transcription factor -
  E0F31_RS09785 (SAMEA3714520_01843) - 1821633..1822730 (-) 1098 WP_054363290.1 sensor histidine kinase -
  E0F31_RS09790 (SAMEA3714520_01844) - 1822730..1823467 (-) 738 WP_023396473.1 ABC transporter permease -
  E0F31_RS09795 (SAMEA3714520_01845) - 1823469..1824353 (-) 885 WP_054363291.1 ABC transporter ATP-binding protein -
  E0F31_RS09800 (SAMEA3714520_01846) - 1824340..1824534 (-) 195 WP_054363292.1 hypothetical protein -
  E0F31_RS09805 (SAMEA3714520_01847) - 1824531..1824737 (-) 207 WP_054363293.1 hypothetical protein -

Sequence

Protein


Download         Length: 336 a.a.        Molecular weight: 37073.01 Da        Isoelectric Point: 5.3212

>NTDB_id=1126292 E0F31_RS09775 WP_000990607.1 1819598..1820608(-) (ccpA) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide


Download         Length: 1011 bp        

>NTDB_id=1126292 E0F31_RS09775 WP_000990607.1 1819598..1820608(-) (ccpA) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, lacI family (LacI)

(8-53)

Periplasmic binding protein-like domain (Peripla_BP_3)

(181-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LZL8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus pneumoniae D39

99.702

100

0.997
  ccpA Streptococcus gordonii str. Challis substr. CH1

87.126

99.405

0.866
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

57.704

98.512

0.568

Multiple sequence alignment