Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   E0F39_RS06235 Genome accession   NZ_LR216060
Coordinates   1160741..1161550 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1155741..1166550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS06210 (SAMEA3713867_01178) - 1156543..1157529 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  E0F39_RS06215 (SAMEA3713867_01179) - 1157848..1159104 (+) 1257 WP_174234207.1 ISL3 family transposase -
  E0F39_RS06220 (SAMEA3713867_01180) - 1159329..1160105 (-) 777 WP_001865265.1 potassium channel family protein -
  E0F39_RS06225 (SAMEA3713867_01181) - 1160152..1160406 (-) 255 WP_001823540.1 type II toxin-antitoxin system RelE family toxin -
  E0F39_RS06230 (SAMEA3713867_01182) relB 1160408..1160650 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  E0F39_RS06235 (SAMEA3713867_01183) vicX 1160741..1161550 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  E0F39_RS06240 (SAMEA3713867_01184) micB 1161552..1162901 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E0F39_RS06245 (SAMEA3713867_01185) micA 1162894..1163598 (-) 705 WP_000722076.1 response regulator YycF Regulator
  E0F39_RS06250 (SAMEA3713867_01186) mutY 1163653..1164828 (-) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  E0F39_RS13050 - 1164925..1165050 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=1126186 E0F39_RS06235 WP_001289493.1 1160741..1161550(-) (vicX) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1126186 E0F39_RS06235 WP_001289493.1 1160741..1161550(-) (vicX) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment