Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   E0F32_RS09650 Genome accession   NZ_LR216050
Coordinates   1786495..1787505 (-) Length   336 a.a.
NCBI ID   WP_000990607.1    Uniprot ID   A0A0B7LZL8
Organism   Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505     
Function   regulate comCDE transcription and transformation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1781495..1792505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F32_RS09625 (SAMEA3431333_01807) - 1781560..1782774 (-) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  E0F32_RS09630 (SAMEA3431333_01808) - 1782930..1783223 (-) 294 WP_000977366.1 hypothetical protein -
  E0F32_RS09635 (SAMEA3431333_01809) - 1783386..1783838 (+) 453 WP_000079148.1 universal stress protein -
  E0F32_RS09640 (SAMEA3431333_01810) - 1783873..1785261 (-) 1389 WP_000453143.1 Cof-type HAD-IIB family hydrolase -
  E0F32_RS09645 (SAMEA3431333_01811) - 1785327..1786289 (+) 963 WP_001124777.1 asparaginase -
  E0F32_RS09650 (SAMEA3431333_01812) ccpA 1786495..1787505 (-) 1011 WP_000990607.1 catabolite control protein A Regulator
  E0F32_RS09655 (SAMEA3431333_01813) - 1787930..1788529 (-) 600 WP_000866719.1 response regulator transcription factor -
  E0F32_RS09660 (SAMEA3431333_01814) - 1788531..1789628 (-) 1098 WP_000893546.1 sensor histidine kinase -
  E0F32_RS09665 (SAMEA3431333_01815) - 1789628..1790365 (-) 738 WP_000832834.1 ABC transporter permease -
  E0F32_RS09670 (SAMEA3431333_01816) - 1790367..1791251 (-) 885 WP_000219348.1 ABC transporter ATP-binding protein -
  E0F32_RS09675 (SAMEA3431333_01817) - 1791238..1791432 (-) 195 WP_000820180.1 hypothetical protein -
  E0F32_RS09680 (SAMEA3431333_01818) - 1791429..1791635 (-) 207 WP_000503437.1 hypothetical protein -

Sequence

Protein


Download         Length: 336 a.a.        Molecular weight: 37073.01 Da        Isoelectric Point: 5.3212

>NTDB_id=1126139 E0F32_RS09650 WP_000990607.1 1786495..1787505(-) (ccpA) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide


Download         Length: 1011 bp        

>NTDB_id=1126139 E0F32_RS09650 WP_000990607.1 1786495..1787505(-) (ccpA) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, lacI family (LacI)

(8-53)

Periplasmic binding protein-like domain (Peripla_BP_3)

(181-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LZL8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus pneumoniae D39

99.702

100

0.997
  ccpA Streptococcus gordonii str. Challis substr. CH1

87.126

99.405

0.866
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

57.704

98.512

0.568

Multiple sequence alignment