Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   EL305_RS12430 Genome accession   NZ_LR134528
Coordinates   2096390..2096839 (+) Length   149 a.a.
NCBI ID   WP_002237378.1    Uniprot ID   A0A0U1RHA9
Organism   Neisseria meningitidis strain NCTC12163     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2096390..2108083 2096390..2096839 within 0


Gene organization within MGE regions


Location: 2096390..2108083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL305_RS12430 (NCTC12163_02079) comP 2096390..2096839 (+) 450 WP_002237378.1 type IV pilin protein Machinery gene
  EL305_RS14195 (NCTC12163_02080) - 2096929..2097323 (-) 395 Protein_2080 5'-nucleotidase -
  EL305_RS12440 (NCTC12163_02081) - 2097394..2097606 (-) 213 WP_002234366.1 SWIM zinc finger family protein -
  EL305_RS12445 (NCTC12163_02082) - 2097896..2098951 (+) 1056 WP_002221681.1 DNA cytosine methyltransferase -
  EL305_RS12450 (NCTC12163_02083) - 2098965..2100611 (+) 1647 WP_002237377.1 TIGR02391 family protein -
  EL305_RS12455 (NCTC12163_02084) - 2100615..2101037 (+) 423 WP_002237376.1 very short patch repair endonuclease -
  EL305_RS14420 - 2101060..2102727 (-) 1668 WP_323208542.1 DUF3418 domain-containing protein -
  EL305_RS14425 - 2103097..2104323 (-) 1227 Protein_2086 DUF3418 domain-containing protein -
  EL305_RS12465 (NCTC12163_02086) lpt3 2104425..2106002 (-) 1578 WP_079885142.1 lipooligosaccharide phosphoethanolamine transferase -
  EL305_RS12470 (NCTC12163_02087) - 2106214..2106396 (-) 183 WP_002223144.1 hypothetical protein -
  EL305_RS12475 (NCTC12163_02088) - 2106440..2108083 (-) 1644 WP_002223143.1 DUF4435 domain-containing protein -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16864.83 Da        Isoelectric Point: 9.7951

>NTDB_id=1124052 EL305_RS12430 WP_002237378.1 2096390..2096839(+) (comP) [Neisseria meningitidis strain NCTC12163]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINTVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=1124052 EL305_RS12430 WP_002237378.1 2096390..2096839(+) (comP) [Neisseria meningitidis strain NCTC12163]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATACAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1RHA9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

99.329

100

0.993
  comP Neisseria meningitidis 8013

98.658

100

0.987
  comP Neisseria subflava NJ9703

48.98

98.658

0.483

Multiple sequence alignment