Detailed information NTG1123996

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: EL323_RS12960
• Genome accession: NZ_LR134526
• Coordinates: 2180739..2181188 (+)
• Length: 149 a.a.
• NCBI ID: WP_002214937.1
• Uniprot ID: A0AA44U8B7
• Organism: Neisseria meningitidis strain NCTC10026
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2182177..2182656	2180739..2181188	flank	989

Gene organization within MGE regions

Location: 2180739..2182656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL323_RS12960 (NCTC10026_02144)	comP	2180739..2181188 (+)	450	WP_002214937.1	type IV pilin protein	Machinery gene
EL323_RS15350 (NCTC10026_02145)	-	2181278..2181621 (-)	344	Protein_2126	5'-nucleotidase	-
EL323_RS12970 (NCTC10026_02146)	-	2181733..2181945 (-)	213	WP_002224145.1	SWIM zinc finger family protein	-
EL323_RS12980 (NCTC10026_02147)	-	2182177..2182650 (+)	474	Protein_2128	IS5/IS1182 family transposase	-

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16834.81 Da
• Isoelectric Point: 9.7951

>NTDB_id=1123996 EL323_RS12960 WP_002214937.1 2180739..2181188(+) (comP) [Neisseria meningitidis strain NCTC10026]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=1123996 EL323_RS12960 WP_002214937.1 2180739..2181188(+) (comP) [Neisseria meningitidis strain NCTC10026]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	100	100	1
comP	Neisseria meningitidis 8013	99.329	100	0.993
comP	Neisseria subflava NJ9703	49.66	98.658	0.49