Detailed information NTG1123985

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EL323_RS09835
• Genome accession: NZ_LR134526
• Coordinates: 1678175..1679035 (+)
• Length: 286 a.a.
• NCBI ID: WP_002221969.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain NCTC10026
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1673175..1684035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL323_RS09810 (NCTC10026_01619)	dapD	1673685..1674506 (-)	822	WP_002216408.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
EL323_RS09815	-	1674516..1674746 (-)	231	WP_025462714.1	hypothetical protein	-
EL323_RS09820 (NCTC10026_01620)	pgi	1674716..1676359 (-)	1644	WP_002220279.1	glucose-6-phosphate isomerase	-
EL323_RS09830 (NCTC10026_01621)	pilG	1676869..1678101 (+)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
EL323_RS09835 (NCTC10026_01622)	pilD	1678175..1679035 (+)	861	WP_002221969.1	prepilin peptidase	Machinery gene
EL323_RS09840 (NCTC10026_01623)	coaE	1679037..1679669 (+)	633	WP_002243235.1	dephospho-CoA kinase	-
EL323_RS09845 (NCTC10026_01624)	-	1679662..1679871 (+)	210	WP_002212333.1	DNA gyrase inhibitor YacG	-
EL323_RS09850 (NCTC10026_01625)	pilF	1679956..1681632 (-)	1677	WP_080541848.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EL323_RS09870 (NCTC10026_01627)	-	1682123..1682569 (-)	447	WP_014581766.1	DUF441 domain-containing protein	-
EL323_RS09875 (NCTC10026_01628)	ispB	1682573..1683547 (-)	975	WP_002235439.1	octaprenyl diphosphate synthase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31302.40 Da
• Isoelectric Point: 8.9527

>NTDB_id=1123985 EL323_RS09835 WP_002221969.1 1678175..1679035(+) (pilD) [Neisseria meningitidis strain NCTC10026]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKKHLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAR
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=1123985 EL323_RS09835 WP_002221969.1 1678175..1679035(+) (pilD) [Neisseria meningitidis strain NCTC10026]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGCAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAAAACATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGCGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACCTTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	95.789	99.65	0.955
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Vibrio campbellii strain DS40M4	44.928	96.503	0.434
pilD	Acinetobacter baumannii D1279779	46.97	92.308	0.434
pilD	Acinetobacter nosocomialis M2	46.97	92.308	0.434