Detailed information NTG1123880

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: EL310_RS11275
• Genome accession: NZ_LR134522
• Coordinates: 1930402..1931667 (+)
• Length: 421 a.a.
• NCBI ID: WP_002220091.1
• Uniprot ID: X5EMG2
• Organism: Neisseria meningitidis strain NCTC3372
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1925402..1936667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL310_RS11250 (NCTC3372_01914)	-	1926133..1927134 (+)	1002	WP_002220087.1	thiamine ABC transporter substrate-binding protein	-
EL310_RS11255 (NCTC3372_01915)	-	1927228..1928076 (+)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
EL310_RS11260 (NCTC3372_01916)	-	1928102..1928587 (+)	486	WP_126375315.1	CinA family protein	-
EL310_RS11265 (NCTC3372_01917)	msrAB	1928689..1930257 (-)	1569	WP_002233356.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
EL310_RS11275 (NCTC3372_01918)	pilA	1930402..1931667 (+)	1266	WP_002220091.1	signal recognition particle-docking protein FtsY	Machinery gene
EL310_RS11290 (NCTC3372_01919)	-	1932256..1932540 (+)	285	WP_002246543.1	GIY-YIG nuclease family protein	-
EL310_RS11300 (NCTC3372_01920)	pilC	1933441..1936602 (+)	3162	WP_269471742.1	PilC family type IV pilus tip adhesin	Machinery gene

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45189.45 Da
• Isoelectric Point: 4.5275

>NTDB_id=1123880 EL310_RS11275 WP_002220091.1 1930402..1931667(+) (pilA) [Neisseria meningitidis strain NCTC3372]
MFSFFRRKKKQETPALEEAQIQETAAKAESETDQVIENIKEDAESLAESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=1123880 EL310_RS11275 WP_002220091.1 1930402..1931667(+) (pilA) [Neisseria meningitidis strain NCTC3372]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAGTCCGAAACCGATCAAGTAATTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGACATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGTAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGACACCTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: X5EMG2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	93.824	100	0.938