Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   EL256_RS00975 Genome accession   NZ_LR134517
Coordinates   203155..203898 (+) Length   247 a.a.
NCBI ID   WP_126442380.1    Uniprot ID   -
Organism   Helicobacter pylori strain NCTC13345     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 198155..208898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL256_RS00950 (NCTC13345_00191) panD 200304..200657 (+) 354 WP_000142244.1 aspartate 1-decarboxylase -
  EL256_RS00955 (NCTC13345_00192) - 200660..200962 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  EL256_RS00960 (NCTC13345_00193) - 200962..201966 (+) 1005 WP_126443606.1 PDZ domain-containing protein -
  EL256_RS00965 (NCTC13345_00194) comB6 201974..203029 (+) 1056 WP_126443607.1 P-type conjugative transfer protein TrbL Machinery gene
  EL256_RS00970 (NCTC13345_00195) comB7 203045..203158 (+) 114 WP_001217870.1 hypothetical protein Machinery gene
  EL256_RS00975 (NCTC13345_00196) comB8 203155..203898 (+) 744 WP_126442380.1 type IV secretion system protein Machinery gene
  EL256_RS00980 (NCTC13345_00197) comB9 203898..204872 (+) 975 WP_126442381.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  EL256_RS00985 (NCTC13345_00198) comB10 204865..206001 (+) 1137 WP_126442382.1 DNA type IV secretion system protein ComB10 Machinery gene
  EL256_RS00990 (NCTC13345_00199) - 206071..207483 (+) 1413 WP_126442383.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  EL256_RS00995 (NCTC13345_00200) gmd 207524..208669 (+) 1146 WP_126442384.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28683.89 Da        Isoelectric Point: 8.9954

>NTDB_id=1123751 EL256_RS00975 WP_126442380.1 203155..203898(+) (comB8) [Helicobacter pylori strain NCTC13345]
MREKPFNSDQMAFLEELLSHQEKHLESKLSGFSVNDLDMQSVFRLERNRLKIAYRLLGLMSFIALILAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=1123751 EL256_RS00975 WP_126442380.1 203155..203898(+) (comB8) [Helicobacter pylori strain NCTC13345]
ATGAGAGAAAAGCCTTTCAACAGCGATCAGATGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAGAG
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGTTGGAAAGGAATCGCTTGAAAATCGCTT
ACAGGCTTTTAGGTTTGATGAGCTTTATCGCTCTTATTTTAGCGATCGTTTTAATCAGCATTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCCCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACGCAAAACAGCATCTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCAAGCGT
GTCCATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTATAGCATCACTGAAATC
GCGCCGACTAACAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.356

100

0.964

Multiple sequence alignment