Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   EL276_RS07985 Genome accession   NZ_LR134516
Coordinates   1728975..1729838 (-) Length   287 a.a.
NCBI ID   WP_126304938.1    Uniprot ID   A0A3S5F6L7
Organism   Neisseria animaloris strain NCTC12227     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1723975..1734838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL276_RS07960 (NCTC12227_01620) - 1725075..1726832 (+) 1758 WP_126304935.1 M61 family metallopeptidase -
  EL276_RS07965 (NCTC12227_01621) - 1726900..1727340 (+) 441 WP_126304936.1 TIGR01244 family sulfur transferase -
  EL276_RS07970 (NCTC12227_01622) yacG 1727395..1727583 (-) 189 WP_085391163.1 DNA gyrase inhibitor YacG -
  EL276_RS07975 (NCTC12227_01623) zapD 1727587..1728354 (-) 768 WP_085391164.1 cell division protein ZapD -
  EL276_RS07980 (NCTC12227_01624) coaE 1728351..1728971 (-) 621 WP_126304937.1 dephospho-CoA kinase -
  EL276_RS07985 (NCTC12227_01625) pilD 1728975..1729838 (-) 864 WP_126304938.1 prepilin peptidase Machinery gene
  EL276_RS07990 (NCTC12227_01626) pilG 1729843..1731081 (-) 1239 WP_107879433.1 type II secretion system F family protein Machinery gene
  EL276_RS07995 (NCTC12227_01627) pilF 1731120..1732799 (-) 1680 WP_085391168.1 type IV-A pilus assembly ATPase PilB Machinery gene
  EL276_RS08005 (NCTC12227_01629) - 1733497..1734117 (+) 621 WP_085391169.1 isochorismatase family protein -

Sequence

Protein


Download         Length: 287 a.a.        Molecular weight: 31302.51 Da        Isoelectric Point: 8.2150

>NTDB_id=1123732 EL276_RS07985 WP_126304938.1 1728975..1729838(-) (pilD) [Neisseria animaloris strain NCTC12227]
MPEWMNLWAPFVVPLSALFGLLVGSFLNVVIYRVPVMMERAWTAFAKEHLGQVLTEEEQQPFNLIKPDSRCPSCQSPVKA
WQNIPVLSYLMLGGKCGSCQTPISKRYPLVELLTGALFAVVAWKYGWSMTTLGGLILTAMLIALTFIDADTQYLPDQLTL
PLVWLGLLFNLNGTFVPLTSAVLGAVCGYMSLWLLCYAYKLLTGKIGMGGGDFKLLAALGAWLGVSVLPVLIFMAALIGL
VAAVIMRVAKGQQFAFGPSLAIAGWIIFIANEQVMTVVGWWLKASGF

Nucleotide


Download         Length: 864 bp        

>NTDB_id=1123732 EL276_RS07985 WP_126304938.1 1728975..1729838(-) (pilD) [Neisseria animaloris strain NCTC12227]
ATGCCTGAATGGATGAATCTCTGGGCACCCTTTGTGGTGCCTCTTTCTGCATTATTTGGCTTGCTAGTAGGCAGTTTTTT
AAATGTAGTAATTTACCGTGTACCAGTAATGATGGAGCGTGCTTGGACGGCATTTGCAAAAGAGCATCTTGGTCAGGTTT
TGACCGAAGAAGAGCAACAGCCGTTTAATTTGATTAAACCTGATTCTCGTTGCCCTTCGTGCCAGTCCCCTGTAAAGGCT
TGGCAAAATATCCCAGTACTCAGTTACCTGATGCTCGGTGGAAAGTGTGGGTCATGTCAAACACCCATCAGCAAACGTTA
TCCTTTAGTAGAGTTGTTAACCGGTGCATTATTTGCAGTAGTTGCTTGGAAATATGGTTGGAGTATGACGACGTTGGGTG
GTTTAATTTTAACCGCTATGTTAATTGCTTTGACCTTTATTGATGCGGATACGCAATATCTTCCTGACCAACTTACACTA
CCTTTGGTTTGGCTGGGATTATTGTTTAATTTGAATGGTACTTTTGTGCCTCTAACGTCGGCTGTTTTAGGTGCGGTTTG
CGGCTACATGAGCTTGTGGCTGTTGTGCTACGCTTATAAATTGCTGACCGGAAAAATAGGCATGGGGGGCGGTGATTTTA
AATTACTCGCTGCTCTGGGAGCATGGTTGGGGGTTAGTGTGTTGCCCGTTTTGATATTTATGGCTGCTTTAATTGGTTTA
GTAGCCGCCGTTATCATGCGTGTGGCAAAAGGCCAGCAGTTCGCTTTCGGCCCCAGTTTGGCGATTGCAGGTTGGATAAT
ATTTATTGCTAATGAGCAGGTTATGACTGTAGTCGGATGGTGGCTGAAAGCTTCGGGATTCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(18-125)

Type IV leader peptidase family (Peptidase_A24)

(135-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S5F6L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

72.662

96.864

0.704
  pilD Vibrio cholerae strain A1552

47.619

95.122

0.453
  pilD Acinetobacter baumannii D1279779

48.669

91.638

0.446
  pilD Acinetobacter nosocomialis M2

47.909

91.638

0.439
  pilD Vibrio campbellii strain DS40M4

46.468

93.728

0.436

Multiple sequence alignment