Detailed information NTG1123704

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: EL265_RS09655
• Genome accession: NZ_LR134515
• Coordinates: 2043280..2043936 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain NCTC10976
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2038280..2048936

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL265_RS09635 (NCTC10976_01941)	nanA	2038654..2039532 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
EL265_RS09640 (NCTC10976_01942)	nagB	2039582..2040385 (+)	804	WP_005602606.1	glucosamine-6-phosphate deaminase	-
EL265_RS09645 (NCTC10976_01943)	nagA	2040437..2041582 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
EL265_RS09650 (NCTC10976_01944)	fumC	2041731..2043125 (-)	1395	WP_005599273.1	class II fumarate hydratase	-
EL265_RS09655 (NCTC10976_01945)	sxy/tfoX	2043280..2043936 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
EL265_RS09660 (NCTC10976_01946)	rpsJ	2044344..2044655 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
EL265_RS09665 (NCTC10976_01947)	rplC	2044681..2045307 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
EL265_RS09670 (NCTC10976_01948)	rplD	2045323..2045925 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
EL265_RS09675 (NCTC10976_01949)	rplW	2045922..2046227 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
EL265_RS09680 (NCTC10976_01950)	rplB	2046248..2047069 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
EL265_RS09685 (NCTC10976_01951)	rpsS	2047097..2047372 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
EL265_RS09690 (NCTC10976_01952)	rplV	2047383..2047715 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
EL265_RS09695 (NCTC10976_01953)	rpsC	2047734..2048441 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
EL265_RS09700 (NCTC10976_01954)	rplP	2048455..2048865 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1123704 EL265_RS09655 WP_005609196.1 2043280..2043936(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain NCTC10976]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1123704 EL265_RS09655 WP_005609196.1 2043280..2043936(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain NCTC10976]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376