Detailed information NTG0112356

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: LA50_RS04615
• Genome accession: NZ_CP009418
• Coordinates: 846145..846729 (+)
• Length: 194 a.a.
• NCBI ID: WP_002234505.1
• Uniprot ID: A1KRU4
• Organism: Neisseria meningitidis strain NM3686
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 841145..851729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA50_RS04580 (LA50_04835)	-	841591..841860 (-)	270	WP_002221591.1	hypothetical protein	-
LA50_RS04585 (LA50_04840)	-	842048..842836 (-)	789	WP_002221592.1	hypothetical protein	-
LA50_RS04590 (LA50_04845)	bioH	842838..843581 (-)	744	WP_002221593.1	pimeloyl-ACP methyl ester esterase BioH	-
LA50_RS04595 (LA50_04850)	-	843580..844305 (+)	726	WP_002221594.1	ComF family protein	-
LA50_RS04600 (LA50_04855)	trmL	844370..844834 (+)	465	WP_002215661.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
LA50_RS12280	-	844845..844967 (+)	123	WP_009346050.1	hypothetical protein	-
LA50_RS04605 (LA50_04860)	-	844964..845683 (+)	720	WP_002221595.1	septal ring lytic transglycosylase RlpA family protein	-
LA50_RS04610 (LA50_04865)	-	845737..846063 (+)	327	WP_002218661.1	PepSY domain-containing protein	-
LA50_RS04615 (LA50_04870)	ruvA	846145..846729 (+)	585	WP_002234505.1	Holliday junction branch migration protein RuvA	Machinery gene
LA50_RS13865 (LA50_04875)	-	846729..846866 (+)	138	WP_002247950.1	hypothetical protein	-
LA50_RS04625 (LA50_04880)	-	846892..848748 (+)	1857	WP_002247949.1	ABC transporter ATP-binding protein	-
LA50_RS04630 (LA50_04885)	rsgA	848753..849676 (+)	924	WP_002247948.1	ribosome small subunit-dependent GTPase A	-
LA50_RS04635 (LA50_04890)	-	849703..850011 (+)	309	WP_002221599.1	exodeoxyribonuclease VII small subunit	-
LA50_RS04640 (LA50_04895)	-	849995..850891 (+)	897	WP_002226001.1	polyprenyl synthetase family protein	-
LA50_RS04645 (LA50_04900)	-	851000..851299 (-)	300	WP_002215645.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20628.88 Da
• Isoelectric Point: 5.8480

>NTDB_id=112356 LA50_RS04615 WP_002234505.1 846145..846729(+) (ruvA) [Neisseria meningitidis strain NM3686]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVSG
IGAKTALGILSAMTADELAQAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHAVTDGLFAAAPAADETEDIVGTLLA
LGYSEREAKAAVKGVPKGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=112356 LA50_RS04615 WP_002234505.1 846145..846729(+) (ruvA) [Neisseria meningitidis strain NM3686]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGCTATGA
GGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAAACATTCCGCCAACTGATTAAGGTCAGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCAGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCCCCGGGAATCGGCAAAAAAACCGCCGAACGCATGGTTTTGGAACTGCGCGGCAAGCTGGTCG
CGCATGCGGTAACGGACGGGCTGTTTGCCGCCGCACCCGCCGCCGACGAAACGGAAGACATCGTCGGCACGCTCCTCGCC
CTCGGTTACAGCGAACGCGAGGCAAAAGCGGCGGTCAAAGGCGTTCCGAAAGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCTTTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• RuvA, C-terminal domain (RuvA_C) (150-192)

• RuvA N terminal domain (RuvA_N) (1-62)

• Helix-hairpin-helix domain (HHH_5) (72-129)

3D structure

• AlphaFold DB: A1KRU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38.5	100	0.397
ruvA	Streptococcus pneumoniae D39	38.5	100	0.397
ruvA	Streptococcus pneumoniae TIGR4	38	100	0.392
ruvA	Bacillus subtilis subsp. subtilis str. 168	35.437	100	0.376