Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EL215_RS00055 Genome accession   NZ_LR134481
Coordinates   11287..11955 (-) Length   222 a.a.
NCBI ID   WP_126469390.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain NCTC10665     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6287..16955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL215_RS00035 (NCTC10665_00007) - 6595..7461 (-) 867 WP_049357040.1 MurR/RpiR family transcriptional regulator -
  EL215_RS00040 (NCTC10665_00008) - 7454..8392 (-) 939 WP_126469384.1 N-acetylmannosamine kinase -
  EL215_RS00045 (NCTC10665_00009) - 8404..9093 (-) 690 WP_126469386.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  EL215_RS00050 (NCTC10665_00010) nagE 9316..10782 (+) 1467 WP_126469388.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  EL215_RS00055 (NCTC10665_00011) crp 11287..11955 (-) 669 WP_126469390.1 cAMP-activated global transcriptional regulator CRP Regulator
  EL215_RS00060 (NCTC10665_00012) - 11972..12190 (-) 219 WP_005695554.1 YheU family protein -
  EL215_RS00065 (NCTC10665_00013) slmA 12212..12865 (-) 654 WP_126469392.1 nucleoid occlusion factor SlmA -
  EL215_RS00070 (NCTC10665_00014) dut 12869..13324 (-) 456 WP_126469394.1 dUTP diphosphatase -
  EL215_RS00075 (NCTC10665_00015) coaBC 13398..14600 (-) 1203 WP_126469396.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  EL215_RS00080 (NCTC10665_00016) radC 14803..15468 (+) 666 WP_126471957.1 RadC family protein -
  EL215_RS00085 (NCTC10665_00017) rpmB 15686..15922 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  EL215_RS00090 (NCTC10665_00018) rpmG 15934..16104 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25114.92 Da        Isoelectric Point: 6.6938

>NTDB_id=1123020 EL215_RS00055 WP_126469390.1 11287..11955(-) (crp) [Haemophilus parainfluenzae strain NCTC10665]
MSEDVELLEEQKPQDDEPQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLAKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=1123020 EL215_RS00055 WP_126469390.1 11287..11955(-) (crp) [Haemophilus parainfluenzae strain NCTC10665]
ATGTCAGAAGATGTAGAATTACTTGAAGAACAAAAGCCTCAGGATGATGAACCGCAACGCGATCCTGCGCTTGATTGGTT
CCTAACACATTGCCATTTACATAAATATCCTGCAAAATCGACTTTAATTCATGCTGGGGAGGATGCCAATATTCTGTATT
TCTTAATTAAAGGAACAGTAATGGTTTCATCAAAAGATGACGAAGGCAAAGAAATGATTTTATCTTATTTGGGGGCTGGA
CAATTTTTTGGTGAAGCGGGTTTATTTGATGAGGGGTCGAAACGTTCTGCTTGGGTAAAAACCAAAACCCCTTGTGAAAT
TGCGGAAATTTCCTATAAAAAATATCGTCAGCTGATTCAAATTAATCCCGAGATTTTAATGTTCCTTACCTCTCAGTTAG
CAAAACGTTTGCAGAATACATCCCGACAAGTCACTAACTTGGCCTTTTTAGATGTGGCAGGGCGTATTGCTCAGGCGCTT
ATGCACTTGGCAAAACAGCCAGAAGCGATGACTCATCCAGATGGTATGCAGATCAAAATTACACGTCAGGAAATTGGTCA
AATGGTGGGCTGTTCTCGTGAAACCGTAGGACGCATAATCAAGATGTTGGAAGATCAAAATCTTATTCATGCGCATGGAA
AAACCATTGTAGTTTATGGTACTCGGTAG

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

86.607

100

0.874
  crp Vibrio cholerae strain A1552

73.786

92.793

0.685
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414

Multiple sequence alignment