Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EL190_RS00185 Genome accession   NZ_LR134395
Coordinates   40881..41555 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus aegyptius strain NCTC8134     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 35881..46555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL190_RS00165 (NCTC8134_00033) hinT 37585..37935 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  EL190_RS00170 (NCTC8134_00034) - 37935..38285 (+) 351 WP_005647993.1 YcfL family protein -
  EL190_RS00175 (NCTC8134_00035) nagZ 38289..39341 (+) 1053 WP_006995612.1 beta-N-acetylhexosaminidase -
  EL190_RS00180 (NCTC8134_00036) rlmC 39338..40516 (+) 1179 WP_006995611.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  EL190_RS00185 (NCTC8134_00037) crp 40881..41555 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  EL190_RS00190 (NCTC8134_00038) - 41540..41791 (-) 252 WP_005647999.1 YheU family protein -
  EL190_RS00195 (NCTC8134_00039) slmA 41813..42469 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  EL190_RS00200 (NCTC8134_00040) dut 42476..42928 (-) 453 WP_006995610.1 dUTP diphosphatase -
  EL190_RS00205 (NCTC8134_00041) coaBC 42976..44178 (-) 1203 WP_006995609.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  EL190_RS00210 (NCTC8134_00042) radC 44342..45007 (+) 666 WP_013527272.1 RadC family protein -
  EL190_RS00215 (NCTC8134_00043) rpmB 45221..45457 (+) 237 WP_006995608.1 50S ribosomal protein L28 -
  EL190_RS00220 (NCTC8134_00044) rpmG 45469..45639 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=1122708 EL190_RS00185 WP_005647998.1 40881..41555(-) (crp) [Haemophilus aegyptius strain NCTC8134]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1122708 EL190_RS00185 WP_005647998.1 40881..41555(-) (crp) [Haemophilus aegyptius strain NCTC8134]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAGGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGGTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment