Detailed information NTG1122466

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EL249_RS04660
• Genome accession: NZ_LR134378
• Coordinates: 1145228..1146811 (+)
• Length: 527 a.a.
• NCBI ID: WP_005674042.1
• Uniprot ID: E7RYF2
• Organism: Lautropia mirabilis strain NCTC12852
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1140228..1151811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL249_RS04640 (NCTC12852_00920)	ffh	1140667..1142058 (-)	1392	WP_040529998.1	signal recognition particle protein	-
EL249_RS04645 (NCTC12852_00921)	-	1142158..1143105 (+)	948	WP_050781913.1	cytochrome C assembly family protein	-
EL249_RS04650 (NCTC12852_00922)	-	1143125..1143415 (+)	291	WP_005674044.1	PP0621 family protein	-
EL249_RS04655 (NCTC12852_00923)	-	1143450..1145231 (+)	1782	WP_005674043.1	two-component system sensor histidine kinase NtrB	-
EL249_RS04660 (NCTC12852_00924)	pilR	1145228..1146811 (+)	1584	WP_005674042.1	sigma-54-dependent transcriptional regulator	Regulator
EL249_RS04665 (NCTC12852_00925)	ampD	1146811..1147380 (+)	570	WP_005674041.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
EL249_RS04670	-	1147555..1147818 (+)	264	WP_126348085.1	hypothetical protein	-
EL249_RS04675 (NCTC12852_00926)	-	1147915..1149111 (+)	1197	WP_126348086.1	hypothetical protein	-
EL249_RS04680 (NCTC12852_00927)	-	1149369..1149932 (+)	564	WP_005674036.1	YggT family protein	-
EL249_RS04685 (NCTC12852_00928)	-	1149989..1150936 (-)	948	WP_005674035.1	carbohydrate kinase family protein	-

Sequence

Protein

• Length: 527 a.a.
• Molecular weight: 56982.08 Da
• Isoelectric Point: 5.4504

>NTDB_id=1122466 EL249_RS04660 WP_005674042.1 1145228..1146811(+) (pilR) [Lautropia mirabilis strain NCTC12852]
MKVTADDDNRLPPGRTPRVLVVDDEESLRELLELTLVGMGLDVDVAEDLSTARAMLERYRYSLCLTDMRLPDGNGLDLVR
LINSQWRDTPVAVITAYASAENAVAALKAGAFDYLNKPVGLDALRALVRSALKLSDTPATKNPVAPPTAQPGGKSTRLLG
TSPAIDAVRASIARMARSMAPVHVTGESGSGKELAARLIHQLSGRAEGPFIAVNCGAIPENLMESEFFGYRKGAFTGADS
DRIGFFMAANGGTLFLDEVADLPLAMQVKLLRAIQEKRIRKVGAVTEEAVDVRIVSATHQNLAQCVAQGRFRQDLFYRLN
VIELRMPALRERQEDVGVLADAILQRLAQRSGLEGVPQLSSMALRYLQSYPFPGNVRELENILERALAFSDGRVINVEDL
GLRPIVTDEKERELDDSLHQGLAAPGGMRPGQGTLAAVPWSAGQGASVSDAAADEGQGTSSMPAASEPRGWKLIDGVPTS
LPDYLDQVERDAILLALERTGQNRTAAARLLGITFRALRYRLQRLGI

Nucleotide

• Length: 1584 bp

>NTDB_id=1122466 EL249_RS04660 WP_005674042.1 1145228..1146811(+) (pilR) [Lautropia mirabilis strain NCTC12852]
ATGAAAGTCACCGCCGACGACGATAACCGTCTGCCCCCCGGCCGGACGCCCCGGGTGCTGGTGGTGGACGACGAGGAAAG
CCTGCGCGAGCTGCTGGAGCTGACGCTGGTGGGCATGGGGCTGGATGTGGACGTGGCCGAGGACCTGTCCACGGCACGTG
CAATGCTGGAGCGCTACCGCTATTCGCTCTGCCTGACCGACATGCGCCTGCCCGACGGCAACGGCCTGGATCTGGTGCGG
CTCATCAACAGCCAGTGGCGCGACACGCCGGTGGCGGTCATCACGGCCTACGCCAGTGCGGAGAACGCCGTGGCGGCGCT
GAAGGCAGGGGCCTTCGATTATCTGAACAAGCCGGTGGGGCTGGATGCACTGCGGGCGCTGGTGCGTTCGGCCCTGAAGC
TCTCGGATACTCCTGCCACGAAGAATCCGGTCGCGCCACCGACGGCGCAGCCCGGGGGCAAGTCCACCCGCCTGCTGGGC
ACGTCGCCCGCCATCGATGCGGTGCGCGCTTCCATCGCGCGCATGGCGCGCAGCATGGCGCCCGTGCACGTCACGGGTGA
GTCCGGTTCCGGCAAGGAGCTGGCGGCTCGGCTCATCCATCAGTTGAGCGGCCGTGCCGAAGGGCCTTTCATCGCCGTGA
ACTGCGGCGCCATCCCCGAGAACCTGATGGAGTCGGAGTTCTTCGGCTACCGCAAGGGGGCGTTCACGGGGGCGGATTCC
GATCGCATCGGCTTCTTCATGGCGGCCAATGGCGGCACGCTGTTCCTGGATGAGGTGGCCGACCTGCCGCTGGCCATGCA
GGTGAAGCTGCTGCGTGCCATCCAGGAAAAGCGCATCCGCAAGGTGGGGGCGGTGACGGAAGAAGCGGTGGATGTGCGCA
TCGTCAGCGCCACCCACCAGAACCTGGCGCAGTGCGTGGCACAGGGACGGTTCCGGCAGGACCTTTTCTACCGGCTCAAC
GTGATCGAGCTGCGCATGCCGGCGCTGCGCGAGCGGCAGGAGGACGTGGGCGTGCTGGCCGATGCCATCCTGCAGCGGCT
GGCACAGCGCAGCGGTCTGGAGGGCGTTCCGCAGCTCTCCAGCATGGCGCTGCGCTACCTGCAGAGCTATCCGTTTCCGG
GCAACGTGCGCGAGCTGGAGAACATCCTGGAACGGGCGCTGGCGTTTTCCGATGGTCGTGTGATCAACGTCGAGGACCTG
GGGCTGCGCCCTATCGTGACCGACGAGAAGGAACGTGAGCTGGATGACTCCCTGCATCAGGGGCTGGCTGCCCCGGGAGG
GATGCGTCCGGGTCAGGGGACATTGGCCGCTGTACCCTGGAGTGCAGGGCAGGGGGCATCGGTGTCCGATGCTGCTGCCG
ACGAAGGGCAGGGCACGTCGTCGATGCCAGCCGCCAGCGAACCGCGCGGCTGGAAGCTGATTGATGGGGTGCCCACCTCA
CTGCCCGATTATCTGGACCAGGTGGAGCGTGATGCCATCCTGCTGGCGCTGGAGCGTACCGGCCAGAATCGTACGGCGGC
GGCGCGGTTGCTGGGCATCACGTTCCGTGCATTGCGTTATCGGCTGCAGCGGCTGGGCATCTGA

Domains

Predicted by InterproScan.

• Bacterial regulatory protein, Fis family (HTH_8) (485-525)

• Response regulator receiver domain (Response_reg) (19-128)

• Sigma-54 interaction domain (Sigma54_activat) (159-324)

3D structure

• AlphaFold DB: E7RYF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	50.784	96.774	0.491
pilR	Acinetobacter baumannii strain A118	43.689	97.723	0.427