Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   EL199_RS11335 Genome accession   NZ_LR134365
Coordinates   2352848..2354368 (-) Length   506 a.a.
NCBI ID   WP_126316086.1    Uniprot ID   -
Organism   Cardiobacterium hominis strain NCTC10426     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2347848..2359368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL199_RS11300 (NCTC10426_02198) ubiE 2348161..2348943 (-) 783 WP_004143269.1 bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE -
  EL199_RS11305 (NCTC10426_02199) - 2348940..2349293 (-) 354 WP_004143268.1 gamma-butyrobetaine hydroxylase-like domain-containing protein -
  EL199_RS11310 (NCTC10426_02200) - 2349277..2349951 (-) 675 WP_004143267.1 HAD family phosphatase -
  EL199_RS11315 (NCTC10426_02201) - 2349948..2350616 (-) 669 WP_004143266.1 HAD family phosphatase -
  EL199_RS11320 (NCTC10426_02202) murB 2350693..2351724 (-) 1032 WP_004143264.1 UDP-N-acetylmuramate dehydrogenase -
  EL199_RS11325 (NCTC10426_02203) - 2351690..2352508 (-) 819 WP_004143261.1 DUF4261 domain-containing protein -
  EL199_RS11330 (NCTC10426_02204) - 2352505..2352801 (-) 297 WP_004143260.1 helix-hairpin-helix domain-containing protein -
  EL199_RS11335 (NCTC10426_02205) pilR 2352848..2354368 (-) 1521 WP_126316086.1 sigma-54 dependent transcriptional regulator Regulator
  EL199_RS11340 (NCTC10426_02206) - 2354397..2355851 (-) 1455 WP_004143257.1 PAS domain-containing sensor histidine kinase -
  EL199_RS11345 - 2355875..2356072 (+) 198 WP_126316087.1 hypothetical protein -
  EL199_RS11350 (NCTC10426_02207) - 2356143..2356913 (-) 771 WP_126316088.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
  EL199_RS11355 (NCTC10426_02208) xth 2356972..2357733 (+) 762 WP_004143254.1 exodeoxyribonuclease III -
  EL199_RS11360 (NCTC10426_02209) zwf 2357890..2359353 (+) 1464 WP_004143253.1 glucose-6-phosphate dehydrogenase -

Sequence

Protein


Download         Length: 506 a.a.        Molecular weight: 55262.09 Da        Isoelectric Point: 6.5094

>NTDB_id=1122324 EL199_RS11335 WP_126316086.1 2352848..2354368(-) (pilR) [Cardiobacterium hominis strain NCTC10426]
MTKALILDDERDICELIEMSLMGQDITCTSVYTIRAAIKALKEERYNFIISDIRLPDGDGLDFLSHVQKHYPGTPVCMIT
AHGNMDTAITALKRGAFDFINKPFDLKQLRSVCKAALKEGHSQSGGASASPAAGGGKKTAPQGGGRSSNKYELIGDAEVM
QKVRAMISKVARSQAPVFIHGESGTGKEVAARSIHHQSNRAEGAFVAVNCGAIPENLVESEFFGYKKGAFTGANQDQDGL
FVAANGGTLFLDEVADLPLSMQVKLLRAIQERAVRPIGGDREEAVDVRIISATHHDLARRVAENKFREDLYYRLNVIGLT
MPPLRERDGDIAILAAHLLAKLARDAGYPLAHLSPAALAKLEAYPFPGNVRELENILERALTFVEGDTIEADGIHLSESR
IPAEPAARPAAPPPVAQPDPRPLRQRAPTADLDEEEITALEQYQPRQKDGPAIPLPNDLENYMQGLERNLLIKALEDCNY
NKTKAAEKLGISFRAMRYKLKKLGID

Nucleotide


Download         Length: 1521 bp        

>NTDB_id=1122324 EL199_RS11335 WP_126316086.1 2352848..2354368(-) (pilR) [Cardiobacterium hominis strain NCTC10426]
ATGACCAAAGCGTTAATCCTTGACGACGAACGCGACATCTGCGAACTCATCGAAATGAGCCTGATGGGGCAGGACATCAC
CTGCACCAGCGTTTACACCATCCGTGCCGCCATCAAAGCGCTCAAAGAAGAGCGCTACAACTTCATCATCTCCGACATCC
GCCTGCCCGATGGCGACGGCCTCGACTTCCTCTCCCACGTACAAAAACACTACCCTGGCACCCCGGTGTGCATGATTACC
GCGCACGGCAACATGGACACCGCCATCACCGCGCTCAAACGCGGCGCCTTCGACTTCATCAACAAACCCTTCGACCTCAA
ACAACTGCGCAGTGTCTGCAAAGCCGCGCTCAAAGAAGGCCACAGCCAAAGCGGCGGCGCGAGTGCCTCACCCGCCGCGG
GCGGCGGCAAAAAAACCGCGCCACAGGGCGGCGGCCGCTCCAGCAACAAATACGAACTCATCGGCGACGCCGAAGTCATG
CAAAAAGTGCGGGCGATGATCAGCAAAGTCGCGCGCTCCCAGGCGCCCGTCTTCATCCACGGCGAATCCGGCACCGGGAA
AGAAGTCGCTGCGCGCTCCATCCACCACCAAAGCAACCGCGCCGAAGGCGCATTCGTCGCCGTAAACTGCGGCGCGATTC
CCGAAAACCTCGTCGAAAGCGAATTCTTCGGCTACAAAAAAGGCGCGTTCACCGGCGCCAACCAGGACCAGGACGGCCTC
TTCGTCGCCGCCAACGGCGGCACATTATTCCTTGACGAAGTCGCCGACCTGCCGCTGTCCATGCAAGTCAAACTGCTGCG
CGCCATCCAGGAGCGCGCGGTGCGCCCCATCGGCGGCGACCGCGAAGAAGCGGTGGACGTGCGCATCATCTCCGCCACCC
ACCACGACCTCGCCCGCCGCGTCGCCGAAAACAAATTCCGCGAAGACCTCTACTACCGCCTGAACGTCATCGGCCTCACC
ATGCCGCCCCTGCGCGAACGCGACGGCGACATCGCCATCCTCGCCGCCCACCTGCTCGCCAAACTGGCACGCGACGCGGG
CTACCCGCTGGCGCACCTCTCACCGGCGGCGCTGGCCAAACTCGAAGCCTACCCCTTCCCCGGCAACGTGCGCGAACTCG
AAAACATCCTCGAACGCGCGCTGACCTTCGTCGAAGGCGACACCATCGAAGCCGACGGCATCCACCTCAGCGAAAGCCGC
ATCCCGGCAGAACCTGCCGCCCGCCCCGCCGCGCCGCCGCCCGTCGCCCAACCCGACCCGCGCCCGCTGCGCCAACGCGC
GCCCACCGCCGACCTTGACGAAGAAGAAATCACCGCCCTCGAACAATACCAGCCGCGCCAAAAAGACGGCCCCGCCATCC
CGCTGCCGAACGACCTCGAAAACTACATGCAGGGACTGGAGCGCAACCTCCTCATCAAGGCGCTGGAAGACTGCAACTAC
AACAAGACCAAAGCCGCCGAAAAACTCGGCATCAGCTTCCGCGCCATGCGCTACAAACTCAAAAAACTCGGCATCGACTG
A

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(153-319)

Response regulator receiver domain (Response_reg)

(5-111)

Bacterial regulatory protein, Fis family (HTH_8)

(466-503)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

48.214

99.605

0.48
  pilR Acinetobacter baumannii strain A118

43.504

100

0.437

Multiple sequence alignment