Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL167_RS04960 Genome accession   NZ_LR134360
Coordinates   1103855..1104484 (+) Length   209 a.a.
NCBI ID   WP_047132848.1    Uniprot ID   A0A143PE14
Organism   Staphylococcus condimenti strain NCTC13827     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1098855..1109484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL167_RS04935 (NCTC13827_01017) - 1099578..1100564 (-) 987 WP_047132843.1 aromatic acid exporter family protein -
  EL167_RS04940 (NCTC13827_01018) map 1100812..1101579 (+) 768 WP_047132844.1 type I methionyl aminopeptidase -
  EL167_RS04945 (NCTC13827_01019) - 1101713..1102108 (+) 396 WP_047132845.1 hypothetical protein -
  EL167_RS04950 (NCTC13827_01020) liaF 1102124..1102825 (+) 702 WP_047132846.1 cell wall-active antibiotics response protein LiaF -
  EL167_RS04955 (NCTC13827_01021) vraS 1102822..1103865 (+) 1044 WP_047132847.1 sensor histidine kinase Regulator
  EL167_RS04960 (NCTC13827_01022) vraR 1103855..1104484 (+) 630 WP_047132848.1 response regulator transcription factor Regulator
  EL167_RS04965 (NCTC13827_01023) - 1104533..1105111 (-) 579 WP_047132849.1 carbonic anhydrase -
  EL167_RS04970 (NCTC13827_01024) - 1105313..1106389 (-) 1077 WP_047132850.1 YihY/virulence factor BrkB family protein -
  EL167_RS04975 (NCTC13827_01025) - 1106509..1106805 (-) 297 WP_047132851.1 hypothetical protein -
  EL167_RS04980 (NCTC13827_01026) - 1106813..1107277 (-) 465 WP_047132852.1 low molecular weight protein-tyrosine-phosphatase -
  EL167_RS04985 (NCTC13827_01027) - 1107513..1107719 (+) 207 WP_047132853.1 DUF1128 family protein -
  EL167_RS04990 (NCTC13827_01028) - 1107758..1108996 (+) 1239 WP_047132854.1 aminopeptidase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23736.22 Da        Isoelectric Point: 4.6397

>NTDB_id=1122245 EL167_RS04960 WP_047132848.1 1103855..1104484(+) (vraR) [Staphylococcus condimenti strain NCTC13827]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELHPDLILMDLLMEDMDGVEATQQIKKDLPDIKVL
MLTSYIEDNEVYRALDAGVDSYILKTTSASDIAEAIRKTQHNESVFEAEVLVKMRNRMNQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHDLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1122245 EL167_RS04960 WP_047132848.1 1103855..1104484(+) (vraR) [Staphylococcus condimenti strain NCTC13827]
ATGACGATTAAAGTGCTATTTGTTGATGACCATGAAATGGTGCGTATCGGCATTTCAAGTTATTTATCGACACAACCAGA
TATTGAAGTGGTAGGGGAAGGAAAGTCTGGAAAAGAAGCTATTGAAAAAGCACATGAACTGCATCCTGATTTAATATTAA
TGGATTTATTGATGGAAGATATGGATGGTGTTGAAGCTACACAGCAAATCAAAAAAGATTTGCCAGATATTAAAGTGTTG
ATGTTAACAAGTTATATTGAAGATAATGAAGTTTATCGTGCACTAGATGCAGGGGTAGACAGTTATATCCTCAAAACAAC
AAGTGCAAGTGACATTGCAGAGGCAATTAGAAAAACACAACATAATGAATCTGTATTTGAAGCAGAAGTACTTGTTAAAA
TGCGTAATCGCATGAACCAACGTGCTGAATTATATGAAATGCTCACTGAAAGAGAGATGGAAATCCTGTTATTAATTGCA
AAAGGGTATTCCAATCAAGAAATTGCAAGTGCTTCTCATATTACAATTAAGACAGTAAAAACGCATGTTAGTAATATTTT
AAGTAAATTAGAAGTGCAAGATAGAACACAAGCAGTTATTTACGCTTTCCAACATGATTTAATCCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A143PE14

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

91.388

100

0.914
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment