Detailed information NTG1122244

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EL167_RS04955
• Genome accession: NZ_LR134360
• Coordinates: 1102822..1103865 (+)
• Length: 347 a.a.
• NCBI ID: WP_047132847.1
• Uniprot ID: A0A143P7E7
• Organism: Staphylococcus condimenti strain NCTC13827
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1097822..1108865

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL167_RS04930 (NCTC13827_01016)	-	1098803..1099528 (+)	726	WP_047132842.1	type 1 glutamine amidotransferase	-
EL167_RS04935 (NCTC13827_01017)	-	1099578..1100564 (-)	987	WP_047132843.1	aromatic acid exporter family protein	-
EL167_RS04940 (NCTC13827_01018)	map	1100812..1101579 (+)	768	WP_047132844.1	type I methionyl aminopeptidase	-
EL167_RS04945 (NCTC13827_01019)	-	1101713..1102108 (+)	396	WP_047132845.1	hypothetical protein	-
EL167_RS04950 (NCTC13827_01020)	liaF	1102124..1102825 (+)	702	WP_047132846.1	cell wall-active antibiotics response protein LiaF	-
EL167_RS04955 (NCTC13827_01021)	vraS	1102822..1103865 (+)	1044	WP_047132847.1	sensor histidine kinase	Regulator
EL167_RS04960 (NCTC13827_01022)	vraR	1103855..1104484 (+)	630	WP_047132848.1	response regulator transcription factor	Regulator
EL167_RS04965 (NCTC13827_01023)	-	1104533..1105111 (-)	579	WP_047132849.1	carbonic anhydrase	-
EL167_RS04970 (NCTC13827_01024)	-	1105313..1106389 (-)	1077	WP_047132850.1	YihY/virulence factor BrkB family protein	-
EL167_RS04975 (NCTC13827_01025)	-	1106509..1106805 (-)	297	WP_047132851.1	hypothetical protein	-
EL167_RS04980 (NCTC13827_01026)	-	1106813..1107277 (-)	465	WP_047132852.1	low molecular weight protein-tyrosine-phosphatase	-
EL167_RS04985 (NCTC13827_01027)	-	1107513..1107719 (+)	207	WP_047132853.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.54 Da
• Isoelectric Point: 5.0629

>NTDB_id=1122244 EL167_RS04955 WP_047132847.1 1102822..1103865(+) (vraS) [Staphylococcus condimenti strain NCTC13827]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIVFFQGMFYTQIFGIPVFLFLNIIVILMCIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQNIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1122244 EL167_RS04955 WP_047132847.1 1102822..1103865(+) (vraS) [Staphylococcus condimenti strain NCTC13827]
ATGAACCATTATATAAGAGCGATAGGTTCAATGTTAATATTGATTTACAGCATTTTAGCTATTTTCTTTTTCATCGATAA
AGTCTTTGTAAATATTGTCTTTTTTCAAGGAATGTTCTATACACAAATTTTCGGAATTCCAGTTTTTTTGTTTTTAAATA
TCATTGTAATATTGATGTGTATTATCGTAGGTTCTGTATTAGCGTATAAAGTGAACCAGCAAAATCATTGGATTAAAGAC
CAAATTGAACATTCTATTGAAGGTGAAGTCGTAGGTATTAATGATCAAAATATCGAACTTTATCAAGAGACGTTAGATAT
CTATCATATGTTGGTACCTTTAAATCAAGAATTGCACCGCTTACGTATTAAAACACAAGATTTAACGAATGAAACTTATA
ATTTAAATGATACAAAAGTAAAAAAAATTATAGAAGATGAACGTCAACGTTTAGCAAGAGAACTGCATGACTCGGTGAGC
CAGCAATTATTTGCTGCAAGTATGATGTTGTCTGCTATAAAGGAAACTAAGTTAGAACCGCCTTTAGATCAACAAATTCC
AACACTTGAAAAGATGGTACAAGATTCACAACTTGAAATGCGTGCTTTATTGCTTCATTTACGTCCATTAGGCTTAAAGG
ACCGTTCATTAGGTGAAGGTATTAAAGACTTGGTTGTAGACTTGCAGAAAAAAGTTCCGATGAAGGTAGTTTATGATATC
GAAGATTTTGAAGTGCCAAAAGGGATAGAAGATCATTTATTCCGAATAACACAAGAAGGTATATCAAACACTTTGCGACA
TGCCGAAGGTACTAAATTGACGATAGATTTATATAATAAAGACGATTATTTACTATTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A143P7E7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	85.591	100	0.856