Detailed information NTG1121636

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EL342_RS02740
• Genome accession: NZ_LR134330
• Coordinates: 570818..572155 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain NCTC13715
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 565818..577155

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL342_RS02715 (NCTC13715_00532)	pgeF	565961..566689 (-)	729	WP_015503650.1	peptidoglycan editing factor PgeF	-
EL342_RS02720 (NCTC13715_00533)	rluD	566686..567648 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EL342_RS02725 (NCTC13715_00534)	-	567794..568819 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EL342_RS02730 (NCTC13715_00535)	-	568976..569221 (+)	246	WP_003102591.1	PP0621 family protein	-
EL342_RS02735 (NCTC13715_00536)	pilS	569211..570803 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
EL342_RS02740 (NCTC13715_00537)	pilR	570818..572155 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EL342_RS02745 (NCTC13715_00538)	thiO	572201..573295 (-)	1095	WP_003141551.1	glycine oxidase ThiO	-
EL342_RS02750 (NCTC13715_00539)	-	573435..573935 (+)	501	WP_016254062.1	GspH/FimT family pseudopilin	-
EL342_RS02755 (NCTC13715_00540)	-	574058..574546 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
EL342_RS02760 (NCTC13715_00541)	pilV	574556..575080 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
EL342_RS02765 (NCTC13715_00542)	-	575089..575904 (+)	816	WP_016254061.1	PilW family protein	-
EL342_RS02770 (NCTC13715_00543)	-	575901..576506 (+)	606	WP_003116263.1	pilus assembly PilX family protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1121636 EL342_RS02740 WP_003094694.1 570818..572155(+) (pilR) [Pseudomonas aeruginosa strain NCTC13715]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1121636 EL342_RS02740 WP_003094694.1 570818..572155(+) (pilR) [Pseudomonas aeruginosa strain NCTC13715]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTACGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGTGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384