Detailed information NTG1120984

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EL344_RS27365
• Genome accession: NZ_LR134309
• Coordinates: 5621967..5623304 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain NCTC12903
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5616967..5628304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL344_RS27340 (NCTC12903_05319)	pgeF	5617110..5617838 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
EL344_RS27345 (NCTC12903_05320)	rluD	5617835..5618797 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EL344_RS27350 (NCTC12903_05321)	-	5618943..5619968 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EL344_RS27355 (NCTC12903_05322)	-	5620125..5620370 (+)	246	WP_003102591.1	PP0621 family protein	-
EL344_RS27360 (NCTC12903_05323)	pilS	5620360..5621952 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
EL344_RS27365 (NCTC12903_05324)	pilR	5621967..5623304 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EL344_RS27370 (NCTC12903_05325)	thiO	5623350..5624444 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
EL344_RS27375 (NCTC12903_05326)	-	5624579..5625088 (+)	510	WP_003102595.1	GspH/FimT family pseudopilin	-
EL344_RS27380 (NCTC12903_05327)	-	5625194..5625700 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
EL344_RS27385 (NCTC12903_05328)	pilV	5625691..5626248 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EL344_RS27390 (NCTC12903_05329)	pilW	5626245..5627069 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EL344_RS27395 (NCTC12903_05330)	pilX	5627066..5627653 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1120984 EL344_RS27365 WP_003094694.1 5621967..5623304(+) (pilR) [Pseudomonas aeruginosa strain NCTC12903]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1120984 EL344_RS27365 WP_003094694.1 5621967..5623304(+) (pilR) [Pseudomonas aeruginosa strain NCTC12903]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCTCAGCG
TCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384