Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL116_RS09765 Genome accession   NZ_LR134304
Coordinates   1973304..1973933 (-) Length   209 a.a.
NCBI ID   WP_000153529.1    Uniprot ID   A0A7U7PW36
Organism   Staphylococcus schweitzeri strain NCTC13712     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1968304..1978933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL116_RS09735 (NCTC13712_01897) - 1968722..1969252 (-) 531 WP_000184380.1 acyl-CoA thioesterase -
  EL116_RS09740 (NCTC13712_01898) - 1969344..1970591 (-) 1248 WP_047550456.1 aminopeptidase -
  EL116_RS09745 (NCTC13712_01899) - 1970603..1970803 (-) 201 WP_047427482.1 DUF1128 domain-containing protein -
  EL116_RS09750 (NCTC13712_01900) - 1970950..1971414 (+) 465 WP_047427479.1 low molecular weight protein-tyrosine-phosphatase -
  EL116_RS09755 (NCTC13712_01901) - 1971421..1971696 (+) 276 WP_000428174.1 YtxH domain-containing protein -
  EL116_RS09760 (NCTC13712_01902) - 1971975..1973192 (+) 1218 WP_047550459.1 YihY/virulence factor BrkB family protein -
  EL116_RS09765 (NCTC13712_01903) vraR 1973304..1973933 (-) 630 WP_000153529.1 two-component system response regulator VraR Regulator
  EL116_RS09770 (NCTC13712_01904) vraS 1973923..1974966 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  EL116_RS09775 (NCTC13712_01905) liaF 1974963..1975664 (-) 702 WP_000149061.1 cell wall-active antibiotics response protein LiaF -
  EL116_RS09780 (NCTC13712_01906) - 1975679..1976065 (-) 387 WP_047427468.1 hypothetical protein -
  EL116_RS09785 (NCTC13712_01907) map 1976286..1977044 (-) 759 WP_047450567.1 type I methionyl aminopeptidase -
  EL116_RS09790 (NCTC13712_01908) - 1977572..1978558 (+) 987 WP_047531879.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23517.28 Da        Isoelectric Point: 5.3889

>NTDB_id=1120792 EL116_RS09765 WP_000153529.1 1973304..1973933(-) (vraR) [Staphylococcus schweitzeri strain NCTC13712]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSKGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1120792 EL116_RS09765 WP_000153529.1 1973304..1973933(-) (vraR) [Staphylococcus schweitzeri strain NCTC13712]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTAGGAGAAGGTGCTTCAGGTAAAGAAGCAATTGCTAAAGCCCATGAGTTAAAACCGGATTTGATTTTAA
TGGATTTACTTATGGATGATATGGATGGTGTAGAAGCGACTACTCAAATTAAAAAAGATTTACCACAAATTAAAGTATTA
ATGTTAACAAGTTTTATTGAAGATAAAGAGGTGTATCGCGCCCTAGATGCAGGTGTTGATAGCTATATTTTAAAAACAAC
GAGTGCAAAAGATATTGCTGATGCAGTTCGTAAAACATCTAAAGGTGAATCTGTATTTGAACCAGAAGTATTAGTAAAAA
TGCGTAACCGTATGAAAAAGCGTGCCGAGTTATATGAAATGTTAACAGAACGTGAAATGGAAATATTATTATTAATTGCC
AAAGGTTATTCTAATCAAGAAATTGCTAGTGCATCACACATTACAATTAAAACGGTTAAGACACATGTAAGTAACATTTT
AAGTAAGTTAGAAGTACAAGATAGAACACAAGCCGTTATTTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PW36

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.043

100

0.99
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment