Detailed information NTG1120782

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: EL116_RS08180
• Genome accession: NZ_LR134304
• Coordinates: 1666898..1669075 (-)
• Length: 725 a.a.
• NCBI ID: WP_047549150.1
• Uniprot ID: A0A2K4AGL5
• Organism: Staphylococcus schweitzeri strain NCTC13712
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1661898..1674075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL116_RS08160 (NCTC13712_01580)	hemW	1662095..1663219 (-)	1125	WP_047549154.1	radical SAM family heme chaperone HemW	-
EL116_RS08165 (NCTC13712_01581)	lepA	1663374..1665197 (-)	1824	WP_047428584.1	translation elongation factor 4	-
EL116_RS08170 (NCTC13712_01582)	rpsT	1665543..1665794 (+)	252	WP_047428582.1	30S ribosomal protein S20	-
EL116_RS08175 (NCTC13712_01583)	holA	1665843..1666817 (-)	975	WP_047428579.1	DNA polymerase III subunit delta	-
EL116_RS08180 (NCTC13712_01584)	comEC	1666898..1669075 (-)	2178	WP_047549150.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL116_RS08185 (NCTC13712_01585)	-	1669080..1669541 (-)	462	WP_000439693.1	ComE operon protein 2	-
EL116_RS08190 (NCTC13712_01586)	comEA	1669633..1670310 (-)	678	WP_047549148.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL116_RS08195 (NCTC13712_01587)	-	1670359..1671075 (-)	717	WP_047549145.1	class I SAM-dependent DNA methyltransferase	-
EL116_RS08200 (NCTC13712_01588)	rsfS	1671078..1671431 (-)	354	WP_047448138.1	ribosome silencing factor	-
EL116_RS08205 (NCTC13712_01589)	yqeK	1671432..1672016 (-)	585	WP_047530078.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
EL116_RS08210 (NCTC13712_01590)	nadD	1672006..1672575 (-)	570	WP_047549143.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
EL116_RS08215 (NCTC13712_01591)	yhbY	1672578..1672868 (-)	291	WP_047549141.1	ribosome assembly RNA-binding protein YhbY	-
EL116_RS08220 (NCTC13712_01592)	aroE	1672873..1673679 (-)	807	WP_047549139.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 725 a.a.
• Molecular weight: 84369.32 Da
• Isoelectric Point: 9.7088

>NTDB_id=1120782 EL116_RS08180 WP_047549150.1 1666898..1669075(-) (comEC) [Staphylococcus schweitzeri strain NCTC13712]
MFYIAISIIVGVLWITNKVLSIFLFILLLFIVFRKSKIIFAPVYLLLIIFSSWYLYISELQLSKHMKSIELNPQINMRVV
ITAFERQSNNSYKGVLKLNDETYPFYLSGKKIEAVSNLENYNCIVKGQFQINDNKYISIKLLNINEQSCYKFDSNNLIEN
HKRFIINRIYNSNINYPNQVIALITGDTKLISEEYLDRVKDIGIYHLLAVSGSHIAAIVFLIYQPLKRLNIPIIIIKTFT
VFILVLFAEYTNYAPSAVRAIIMTCIILIIPNQIRFNCINLLSTAFIIMFISNPQIIYNVGFQFSFIISFFIILLLPFIQ
KLSKIQSLLVITFVAQLASFIVSIPQFHQVQWIGFVTNLVFVPYYSMILFPLSIIFFIISHFPIEFTPLNDLVNLSFDFH
NWLLYLFIKINHTNFLIPKINTWTLVVLIIYIYCILWLLANRKFKLTFIYTMVLFMLFFVFPTNQHHRITMLNVGQGDSI
LYEAGNNKNVLIDTGGRVVTDNAQNNFSISKYHILPTLNERGINKLEYLILTHPHNDHIGEVEYIMRHLKIKYLVIYSSS
YNDRMLLSLSNLSKRYNIKLLDVRQVRQFRIGESDFTFLNSYIQGSQDKNEYSIVTLIKYHNKKVLLMGDATKNNEEILL
KKYRLPKVDILKVGHHGSKTSSSAQFIEAVQPKISLISSGKNNIYHLPNKEIINRLNSFHSHIYDSQHNGQVTIDLDENL
NVMLN

Nucleotide

• Length: 2178 bp

>NTDB_id=1120782 EL116_RS08180 WP_047549150.1 1666898..1669075(-) (comEC) [Staphylococcus schweitzeri strain NCTC13712]
TTGTTTTATATTGCTATATCAATAATAGTAGGAGTACTTTGGATAACAAACAAAGTGCTCTCTATATTCCTTTTTATTTT
ATTATTATTCATTGTTTTTCGAAAAAGTAAAATTATATTTGCTCCTGTTTATCTCTTACTAATTATTTTCTCCTCATGGT
ATTTATATATTTCTGAACTTCAATTATCAAAACATATGAAATCAATTGAATTAAATCCACAAATTAACATGAGAGTCGTT
ATCACAGCATTTGAACGACAAAGTAATAATAGCTACAAAGGGGTGTTAAAGCTAAACGATGAGACATACCCATTCTATTT
ATCAGGCAAAAAGATTGAAGCTGTATCAAATCTTGAAAACTATAATTGTATTGTAAAAGGTCAATTTCAAATTAATGACA
ATAAATATATTTCTATTAAACTACTTAATATAAATGAGCAAAGTTGTTATAAATTCGATAGTAATAATTTGATAGAAAAC
CACAAGCGATTTATTATAAATCGAATATATAATTCAAACATAAATTATCCTAATCAAGTGATTGCTTTGATTACTGGTGA
TACAAAGCTCATCAGTGAGGAATATTTAGATCGAGTTAAAGATATAGGTATATATCATTTACTTGCAGTTAGTGGTTCGC
ATATTGCTGCAATTGTCTTTTTAATTTATCAGCCGTTAAAACGTTTAAACATCCCCATAATAATCATTAAAACTTTCACT
GTTTTTATACTGGTTTTGTTTGCAGAGTATACAAATTACGCACCTAGTGCAGTTAGAGCTATTATTATGACATGTATTAT
TTTAATAATACCTAATCAAATAAGATTTAATTGTATAAATTTATTATCGACAGCATTTATTATTATGTTTATTTCGAATC
CTCAGATAATTTACAATGTTGGATTTCAATTTTCGTTTATTATTTCATTTTTCATCATTTTATTATTACCTTTTATACAG
AAATTATCGAAAATACAGTCTTTATTGGTCATTACTTTTGTTGCGCAATTAGCTTCTTTTATAGTTTCGATACCTCAATT
TCATCAAGTACAATGGATAGGATTTGTAACAAATCTCGTTTTTGTTCCATATTATTCAATGATATTATTTCCTCTATCGA
TTATTTTCTTTATTATCAGCCATTTTCCAATAGAATTTACTCCCTTGAATGATTTGGTTAATCTTAGCTTCGATTTTCAC
AATTGGTTATTATATTTATTTATTAAAATAAATCACACGAATTTTTTAATTCCGAAAATTAATACGTGGACACTTGTTGT
ACTAATAATCTACATTTATTGTATTTTGTGGCTATTAGCTAATAGGAAATTCAAACTAACTTTCATCTATACTATGGTTT
TATTTATGTTATTTTTCGTATTTCCAACAAATCAACATCATAGAATTACGATGTTAAATGTAGGACAAGGAGACAGTATT
TTATATGAAGCGGGAAATAATAAAAATGTTTTAATTGATACTGGAGGTAGAGTGGTAACTGATAATGCTCAAAATAACTT
TTCGATTTCCAAATATCATATTTTACCTACTTTAAATGAAAGAGGAATTAATAAATTAGAATATTTGATATTAACCCATC
CTCATAATGACCATATTGGTGAAGTAGAATATATTATGAGGCACTTAAAAATAAAATATTTAGTGATTTATAGTAGTAGC
TATAATGATAGGATGTTGTTATCTTTATCTAATTTATCTAAAAGATATAATATTAAACTTTTAGATGTGAGACAAGTAAG
ACAATTTAGAATAGGAGAAAGTGATTTTACATTTTTAAATAGTTATATTCAGGGTAGCCAAGACAAAAATGAGTATTCAA
TCGTTACTTTGATTAAATATCATAATAAGAAAGTATTATTAATGGGAGATGCAACTAAAAATAATGAAGAGATATTACTG
AAGAAATATCGACTACCAAAAGTTGATATTCTTAAAGTAGGACATCACGGAAGTAAGACTAGCAGTTCAGCACAATTCAT
TGAAGCGGTACAACCTAAAATTAGCTTGATTTCATCTGGTAAAAATAACATATATCATCTACCTAATAAAGAGATAATAA
ATAGATTAAATAGTTTTCATAGTCATATTTATGATTCACAACATAATGGACAAGTTACAATTGATTTAGATGAAAATTTA
AATGTTATGTTAAATTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (183-440)

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

3D structure

• AlphaFold DB: A0A2K4AGL5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	63.573	99.586	0.633
comEC	Staphylococcus aureus MW2	63.435	99.586	0.632