Detailed information NTG1120564

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EL096_RS07250
• Genome accession: NZ_LR134294
• Coordinates: 1352269..1353279 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain NCTC12977
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1347269..1358279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL096_RS07225 (NCTC12977_01407)	-	1348422..1348727 (-)	306	WP_000977370.1	hypothetical protein	-
EL096_RS07230 (NCTC12977_01408)	-	1348889..1349341 (+)	453	WP_000079148.1	universal stress protein	-
EL096_RS07235 (NCTC12977_01409)	-	1349376..1350764 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EL096_RS07240 (NCTC12977_01410)	-	1350830..1351792 (+)	963	WP_001124777.1	asparaginase	-
EL096_RS07245 (NCTC12977_01411)	-	1351789..1352205 (-)	417	WP_061849636.1	hypothetical protein	-
EL096_RS07250 (NCTC12977_01412)	ccpA	1352269..1353279 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EL096_RS07255 (NCTC12977_01413)	-	1353704..1354303 (-)	600	WP_054387484.1	response regulator transcription factor	-
EL096_RS07260 (NCTC12977_01414)	-	1354305..1355402 (-)	1098	WP_114880769.1	sensor histidine kinase	-
EL096_RS07265 (NCTC12977_01415)	-	1355402..1356139 (-)	738	WP_000832916.1	ABC transporter permease	-
EL096_RS07270 (NCTC12977_01416)	-	1356141..1357025 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
EL096_RS07275 (NCTC12977_01417)	-	1357012..1357206 (-)	195	WP_000820189.1	hypothetical protein	-
EL096_RS11865	-	1357203..1357409 (-)	207	Protein_1365	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1120564 EL096_RS07250 WP_000990607.1 1352269..1353279(-) (ccpA) [Streptococcus pneumoniae strain NCTC12977]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1120564 EL096_RS07250 WP_000990607.1 1352269..1353279(-) (ccpA) [Streptococcus pneumoniae strain NCTC12977]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568