Detailed information NTG1120120

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EL070_RS07985
• Genome accession: NZ_LR134284
• Coordinates: 1501191..1502192 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NCTC8232
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1496191..1507192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL070_RS07970 (NCTC8232_01606)	thrS	1496362..1498305 (-)	1944	WP_111677101.1	threonine--tRNA ligase	-
EL070_RS07975 (NCTC8232_01608)	-	1498726..1500060 (-)	1335	WP_111705496.1	glycosyltransferase family 4 protein	-
EL070_RS07980 (NCTC8232_01609)	-	1500062..1501060 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
EL070_RS07985 (NCTC8232_01610)	ccpA	1501191..1502192 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
EL070_RS07990 (NCTC8232_01611)	-	1502366..1503451 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
EL070_RS07995 (NCTC8232_01612)	-	1503500..1504165 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
EL070_RS08000 (NCTC8232_01613)	-	1504176..1504553 (+)	378	WP_002985686.1	VOC family protein	-
EL070_RS08005 (NCTC8232_01614)	-	1504698..1505624 (+)	927	WP_002990711.1	glycosyltransferase family 2 protein	-
EL070_RS08010 (NCTC8232_01615)	-	1505835..1506518 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1120120 EL070_RS07985 WP_002985680.1 1501191..1502192(-) (ccpA) [Streptococcus pyogenes strain NCTC8232]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1120120 EL070_RS07985 WP_002985680.1 1501191..1502192(-) (ccpA) [Streptococcus pyogenes strain NCTC8232]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGATTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559