Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   LOA_RS06405 Genome accession   NZ_CP004006
Coordinates   1317185..1318504 (+) Length   439 a.a.
NCBI ID   WP_025385618.1    Uniprot ID   -
Organism   Legionella oakridgensis ATCC 33761 = DSM 21215     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1312185..1323504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOA_RS06385 (Loa_01428) - 1312480..1312821 (-) 342 WP_025385616.1 zinc ribbon domain-containing protein YjdM -
  LOA_RS06390 (Loa_01429) - 1312960..1313760 (-) 801 WP_202961899.1 histone deacetylase family protein -
  LOA_RS13750 (Loa_01430) - 1313908..1315077 (-) 1170 WP_025385617.1 hypothetical protein -
  LOA_RS14685 (Loa_01431) - 1315268..1315438 (-) 171 WP_155831636.1 hypothetical protein -
  LOA_RS06400 (Loa_01433) - 1315737..1317188 (+) 1452 WP_238551355.1 sensor histidine kinase -
  LOA_RS06405 (Loa_01434) pilR 1317185..1318504 (+) 1320 WP_025385618.1 sigma-54-dependent transcriptional regulator Regulator
  LOA_RS06410 (Loa_01436) - 1318561..1319936 (-) 1376 Protein_1324 M48 family metalloprotease -
  LOA_RS06415 (Loa_01437) ribD 1320075..1321154 (+) 1080 WP_025385619.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  LOA_RS06420 (Loa_01438) - 1321139..1321747 (+) 609 WP_025385620.1 riboflavin synthase -
  LOA_RS06425 (Loa_01439) - 1321804..1323012 (+) 1209 WP_025385621.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 48930.69 Da        Isoelectric Point: 7.3720

>NTDB_id=112000 LOA_RS06405 WP_025385618.1 1317185..1318504(+) (pilR) [Legionella oakridgensis ATCC 33761 = DSM 21215]
MSNEKVLVIDDEPDIRELLSLTLKRMGLSCDIAAGFEEGITCIKNNEYFLVLTDMRLPDGDGYEIVRYIQKQSPQLPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPVDLTMLKSLVNTALRMYQRPETPDELLLGKSEIMQTLRQNIRKLARSQAPVFIQG
ESGVGKELVARLIHAYGPRNEKPFIAINCGAIPSELMESEFFGHKKGSFTGAFNDKQGLFVAAAGGTLFLDEVAELPLAM
QVKLLRAIQEKAVKPVGALNEIPVDVRILSASNKNLQDEIAAGRFRQELYYRINVIELHVPALQERASDIPLLADNILQK
LAKEQEQKPPVLSKAALQALQAYSFPGNVRELENILERAMTLCNGKTIDVTDLQLSQTQQRMLHTPTETLNLEKALQAHE
KELILHALEKTKWNRTAAARLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=112000 LOA_RS06405 WP_025385618.1 1317185..1318504(+) (pilR) [Legionella oakridgensis ATCC 33761 = DSM 21215]
ATGAGCAATGAAAAAGTGCTCGTCATTGATGACGAGCCTGATATTCGTGAATTGCTATCCCTCACATTAAAACGCATGGG
GTTATCCTGTGATATTGCCGCAGGATTTGAAGAGGGCATTACCTGCATAAAAAACAATGAATATTTTCTGGTATTAACGG
ACATGCGTCTTCCCGATGGAGATGGGTATGAGATCGTTCGTTATATACAAAAACAATCTCCTCAACTGCCAGTGGCAGTG
ATTACAGCTTATGGGAATGTGGAGGGTGCTGTGAACACCTTAAAAGCGGGCGCTTTTGATTATGTTTCCAAACCGGTCGA
TTTAACCATGCTTAAATCTCTCGTTAATACGGCATTACGAATGTATCAGCGGCCGGAAACACCGGATGAATTACTCTTAG
GCAAGAGTGAGATCATGCAAACATTACGGCAAAATATTCGTAAGTTAGCACGTAGCCAGGCTCCAGTGTTTATTCAGGGT
GAATCAGGCGTCGGCAAGGAATTGGTTGCTCGCCTTATTCATGCGTATGGTCCAAGAAATGAAAAGCCGTTTATTGCAAT
CAATTGTGGCGCAATCCCAAGTGAATTAATGGAGTCTGAGTTTTTTGGACATAAAAAAGGAAGTTTTACAGGTGCCTTTA
ATGATAAACAGGGATTATTTGTAGCGGCGGCTGGAGGTACTTTATTTCTTGATGAAGTGGCGGAGTTACCCTTAGCCATG
CAAGTGAAACTATTACGTGCGATTCAGGAAAAAGCCGTCAAACCTGTCGGTGCATTAAATGAAATCCCTGTGGATGTCCG
TATTTTAAGTGCAAGCAATAAAAATCTACAGGACGAGATTGCTGCCGGTCGATTTCGGCAAGAATTATATTATCGAATTA
ATGTGATTGAGTTGCATGTTCCCGCTTTACAGGAACGAGCTTCTGATATTCCTTTGCTCGCGGATAATATTTTACAAAAA
CTTGCCAAAGAGCAAGAACAAAAACCGCCAGTATTATCAAAAGCAGCTTTACAAGCATTGCAAGCATACTCTTTCCCAGG
AAATGTACGTGAGCTTGAAAATATATTAGAACGTGCTATGACGTTGTGTAATGGGAAGACGATTGATGTCACCGATTTAC
AGCTTTCGCAAACACAGCAACGCATGTTGCACACGCCAACTGAAACGCTGAATCTTGAGAAAGCATTGCAAGCACATGAA
AAAGAATTAATTTTGCATGCCTTAGAAAAAACAAAATGGAATCGTACGGCAGCCGCAAGATTACTGGGAGTCAGTTTTCG
CACGTTGCGTTATCGATTAAAAAAGCTGGGACTTGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(132-298)

Bacterial regulatory protein, Fis family (HTH_8)

(400-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

60.225

100

0.61
  pilR Acinetobacter baumannii strain A118

49.237

100

0.515
  luxO Vibrio cholerae strain A1552

36.878

100

0.371

Multiple sequence alignment