Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   EL077_RS06935 Genome accession   NZ_LR134273
Coordinates   1482507..1483859 (-) Length   450 a.a.
NCBI ID   WP_126436911.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi strain NCTC12091     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1477507..1488859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL077_RS06920 (NCTC12091_01410) rnc 1478325..1479017 (-) 693 WP_012677641.1 ribonuclease III -
  EL077_RS06925 (NCTC12091_01411) - 1479276..1480790 (-) 1515 WP_159334850.1 helix-turn-helix domain-containing protein -
  EL077_RS06930 (NCTC12091_01412) vicX 1481694..1482503 (-) 810 WP_111692627.1 MBL fold metallo-hydrolase Regulator
  EL077_RS06935 (NCTC12091_01413) vicK 1482507..1483859 (-) 1353 WP_126436911.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL077_RS06940 (NCTC12091_01414) vicR 1483852..1484562 (-) 711 WP_012515994.1 response regulator YycF Regulator
  EL077_RS06945 (NCTC12091_01415) - 1484761..1485780 (-) 1020 WP_126436913.1 DUF3114 domain-containing protein -
  EL077_RS06950 (NCTC12091_01416) - 1485826..1487088 (-) 1263 WP_043052257.1 AMP-binding protein -
  EL077_RS06955 (NCTC12091_01417) - 1487078..1488193 (-) 1116 WP_126436915.1 acetyl-CoA C-acyltransferase -
  EL077_RS06960 (NCTC12091_01418) - 1488190..1488729 (-) 540 WP_111692629.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51545.95 Da        Isoelectric Point: 5.5557

>NTDB_id=1119763 EL077_RS06935 WP_126436911.1 1482507..1483859(-) (vicK) [Streptococcus equi subsp. equi strain NCTC12091]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHEMRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1119763 EL077_RS06935 WP_126436911.1 1482507..1483859(-) (vicK) [Streptococcus equi subsp. equi strain NCTC12091]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTGGTTGTTGTACTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGCGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGATGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCACTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTAGATGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
CCTCTCAAGAATTGATAATCATGTGACACAGTTATCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATTACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGCATAC
CAAAGAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGAACTGGT
CTAGGCTTAGCGATTGCTAAAGAAATTATTAAGCAGCACCGCGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.43

92

0.676
  micB Streptococcus pneumoniae Cp1015

66.588

94.444

0.629

Multiple sequence alignment