Detailed information NTG1119756

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: EL077_RS04805
• Genome accession: NZ_LR134273
• Coordinates: 1019634..1020371 (+)
• Length: 245 a.a.
• NCBI ID: WP_111692437.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. equi strain NCTC12091
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1014634..1025371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL077_RS04775 (NCTC12091_00971)	-	1015091..1015996 (-)	906	WP_043025804.1	diacylglycerol/lipid kinase family protein	-
EL077_RS04780 (NCTC12091_00972)	trhA	1016106..1016756 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
EL077_RS04785 (NCTC12091_00973)	-	1016740..1017195 (-)	456	WP_037578258.1	DUF1836 domain-containing protein	-
EL077_RS04790 (NCTC12091_00974)	-	1017455..1018210 (+)	756	WP_126436661.1	class I SAM-dependent methyltransferase	-
EL077_RS04795 (NCTC12091_00975)	-	1018238..1018576 (+)	339	WP_126436663.1	cupin domain-containing protein	-
EL077_RS04800 (NCTC12091_00976)	-	1018578..1018883 (+)	306	WP_012677981.1	AraC family ligand binding domain-containing protein	-
EL077_RS04805 (NCTC12091_00977)	comE/blpR	1019634..1020371 (+)	738	WP_111692437.1	response regulator transcription factor	Regulator
EL077_RS04810 (NCTC12091_00978)	-	1020741..1020941 (+)	201	WP_042670621.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
EL077_RS04815 (NCTC12091_00979)	-	1021008..1021862 (+)	855	WP_126437211.1	ABC transporter ATP-binding protein	-
EL077_RS09930 (NCTC12091_00980)	-	1021868..1022491 (+)	624	WP_337660730.1	hypothetical protein	-
EL077_RS09935 (NCTC12091_00981)	-	1022503..1023021 (+)	519	WP_337660731.1	hypothetical protein	-
EL077_RS04825 (NCTC12091_00982)	-	1023283..1023513 (+)	231	WP_111692439.1	Blp family class II bacteriocin	-
EL077_RS04835 (NCTC12091_00983)	-	1024306..1024986 (+)	681	WP_228269169.1	thioredoxin family protein	-
EL077_RS09940	-	1025027..1025158 (+)	132	WP_228269170.1	LPXTG cell wall anchor domain-containing protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28904.32 Da
• Isoelectric Point: 7.8796

>NTDB_id=1119756 EL077_RS04805 WP_111692437.1 1019634..1020371(+) (comE/blpR) [Streptococcus equi subsp. equi strain NCTC12091]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILYSQNERIEFYGFLSEVLKQDPRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=1119756 EL077_RS04805 WP_111692437.1 1019634..1020371(+) (comE/blpR) [Streptococcus equi subsp. equi strain NCTC12091]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATTAGAAAGCGTGAC
CCTTACGCTCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGTATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATCCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.041	98.776	0.445
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367