Detailed information NTG1118782

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: EL022_RS12715
• Genome accession: NZ_LR134173
• Coordinates: 2990686..2993418 (+)
• Length: 910 a.a.
• NCBI ID: WP_028380218.1
• Uniprot ID: A0A0W0SAJ9
• Organism: Legionella cherrii strain NCTC11976
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2985686..2998418

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL022_RS12700 (NCTC11976_02645)	-	2986435..2987418 (-)	984	WP_237761305.1	hypothetical protein	-
EL022_RS12705 (NCTC11976_02646)	-	2987690..2988955 (-)	1266	WP_028380220.1	serine hydrolase domain-containing protein	-
EL022_RS12710 (NCTC11976_02647)	gltX	2989094..2990509 (-)	1416	WP_028380219.1	glutamate--tRNA ligase	-
EL022_RS12715 (NCTC11976_02648)	letS	2990686..2993418 (+)	2733	WP_028380218.1	ATP-binding protein	Regulator
EL022_RS12720 (NCTC11976_02649)	-	2993495..2994733 (+)	1239	WP_028380217.1	6-phosphofructokinase	-
EL022_RS12725 (NCTC11976_02650)	pilA2	2995042..2995473 (+)	432	WP_028380216.1	pilin	Machinery gene
EL022_RS12730 (NCTC11976_02651)	-	2995540..2995869 (+)	330	WP_028380215.1	BolA family protein	-
EL022_RS12735 (NCTC11976_02652)	-	2996076..2996417 (+)	342	WP_028380214.1	hypothetical protein	-
EL022_RS12740 (NCTC11976_02653)	-	2996663..2998069 (+)	1407	WP_028380213.1	APC family permease	-
EL022_RS12745 (NCTC11976_02654)	-	2998223..2998402 (-)	180	WP_028380212.1	Trm112 family protein	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 102748.09 Da
• Isoelectric Point: 7.3281

>NTDB_id=1118782 EL022_RS12715 WP_028380218.1 2990686..2993418(+) (letS) [Legionella cherrii strain NCTC11976]
MKSIGIKYQLRITTLIPAFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRRDDRTLQGLINASTINPE
VKALAFYSSDGQLLAYRGGKHSLNKPFNPPKFTGDYIESKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMATRADDI
LGWLSIDIDTRSMIIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYLPISRLRRSMKQILRNEFETEIKTTSPGELGII
EQGCAHLQKKYLETIRDLNQHIEIATEDLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKASAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLTLAAPNAHKKGIDLIPITDV
SVPKIVLGDPFRIKQFITNLVTNAVKFTDHGYVLVRTKVEQETDKDYTLCITITDTGLGISPEDQSKLFTAFNQADTSIT
RRYGGSGLGLVICKKLCEEMHGRISFTSELNKGSSFTAQVKVEKLVAYEIEKNQIHPFAHFKMLCFDDNSLHLEALCNGL
GYWGIQCIPVNSFNRLASALENNKDCNIAFLNINKGYEQKIAKIIAEHNYFPYVLISKWLINDYTALGAQGFLYKPISIQ
KLQDVIESLTSQENIEKPVNHELDGLREQLRFMHPDLLIAEDNPVNKMLLDSLLGTHANMTAVDDGEMAVSACNDKKYDL
ILLDLQMPKVNGLEAARLIRQKSQLNRHTPIVLISANGSDVNSIDLKKSGVDFCLQKPVDEKQLLTQILRITDKAKHAAI
DWQLCVQKVSGNQALAEEFLSRFVEELHKNREEFIQLMHDKNIKKIGEAAHKLHGACCFSGVPTLQKKVVQVEKLAAHAA
SIEELATPFAELIQSIDAVINEYEHQKVRI

Nucleotide

• Length: 2733 bp

>NTDB_id=1118782 EL022_RS12715 WP_028380218.1 2990686..2993418(+) (letS) [Legionella cherrii strain NCTC11976]
TTGAAAAGCATAGGTATCAAGTATCAACTGAGAATTACCACCCTAATTCCAGCCTTTTTAGTCGCCCTGCTTCTCGCTAT
TTTTTATAATGGACTGTTTGGTAATGATTTAAAACAGCACATGTCCCGTCTGGGCGAAGCATACATCCGTCAATTACTTC
CTGCAGCACAATACGCCATGCTTCGACGTGACGATCGCACGTTGCAAGGGTTAATTAATGCATCCACAATCAATCCAGAG
GTCAAGGCCCTCGCTTTTTACAGTAGTGACGGACAACTGCTGGCTTACCGCGGCGGCAAACATTCTCTGAATAAACCTTT
CAATCCTCCTAAATTTACGGGGGATTATATTGAAAGTAAGCAAATTAATCCTTTTACCATTAACTTCATCGCACCCGTTA
CTATCCCTAAATTCAATCTTTATTCCAATTCGTCTTTTAAGAACATCCTCAGCCCAATGGCCACTCGTGCCGATGATATT
TTAGGTTGGTTATCCATTGACATCGATACTCGCTCGATGATCATCAAACGTTATCAAATGCTCATAGTAACCATTTTTAT
TACTCTTTTTGGTTTGCTCATGGGATTGACCATCCACTACTTTCTCTCTAAGCGGATTTATCTACCCATTTCCCGTTTAC
GTCGGAGCATGAAACAAATTTTACGCAATGAGTTCGAAACAGAAATCAAAACAACGAGCCCAGGTGAACTCGGCATCATT
GAGCAAGGATGTGCCCATTTGCAAAAAAAATACCTCGAAACAATACGCGACTTAAATCAACATATCGAAATCGCCACTGA
AGATTTACAGCAAAGTCTTGAACTGTTAGAAGAAAAAAATATTGAGCTTTCGCTTGAGAAGAAAAAAATAGAAGAGAAAA
GTCGACAAAAATCAGAATTTATTGCCAATATGAGTCATGAAATCCGCACACCAATGAATGGTGTTATTGGCTTTACTAAT
GTTTTATTGGAAAGCAAGCTTGATCCCCTGCAATTAGATTATGTAAAAACAATCAAAGCTTCTGCACAAGACTTGTTAGG
AATTATTAATGATATCCTCGATTTCTCTAAAATTGATGCGGGAAAACTTCACCTCGATTGCATCCCCTTAAATATCCGTC
ATTGTATCGATGAAGTGCTTACCCTTGCAGCACCAAATGCTCATAAAAAAGGGATTGATTTAATCCCAATAACCGATGTA
AGTGTACCTAAAATTGTTTTAGGTGATCCCTTTAGAATCAAACAATTTATCACCAATCTTGTGACTAATGCGGTTAAATT
TACCGATCATGGTTATGTATTGGTCCGCACTAAAGTAGAACAAGAAACAGATAAAGATTACACTTTATGCATCACAATCA
CTGATACTGGCTTAGGTATTTCACCAGAGGATCAAAGTAAATTATTTACTGCATTTAACCAGGCCGATACAAGCATTACT
CGTCGTTATGGCGGTTCAGGCCTAGGATTAGTCATTTGTAAAAAACTCTGTGAAGAAATGCATGGACGTATTAGCTTTAC
CAGCGAGCTCAATAAAGGTTCTAGCTTCACTGCTCAGGTGAAAGTTGAAAAGTTAGTTGCCTATGAAATAGAAAAAAATC
AAATACACCCCTTCGCGCATTTTAAAATGTTATGCTTTGATGATAATTCGCTCCATTTGGAAGCACTATGCAATGGCTTA
GGTTATTGGGGAATTCAATGTATTCCGGTCAATTCGTTTAACCGTCTTGCGAGTGCTCTTGAGAATAACAAAGACTGTAA
TATTGCTTTTCTCAATATCAACAAAGGTTATGAACAAAAGATAGCCAAAATCATTGCCGAACATAACTATTTTCCATACG
TGCTCATTTCCAAATGGCTTATTAATGATTACACAGCACTTGGAGCCCAGGGCTTTCTATATAAACCCATCAGCATTCAA
AAACTTCAAGATGTTATTGAATCCCTCACTAGCCAAGAGAACATTGAAAAACCGGTCAATCATGAATTGGATGGTTTAAG
AGAACAATTACGTTTTATGCACCCTGATTTACTCATTGCTGAAGACAATCCAGTAAACAAAATGCTTCTGGACTCTTTAT
TGGGCACTCATGCAAATATGACTGCAGTTGATGACGGTGAAATGGCGGTATCGGCGTGTAATGACAAAAAATACGACCTC
ATTTTGCTCGATTTGCAGATGCCTAAAGTCAATGGATTAGAGGCAGCTCGACTCATTCGACAAAAATCACAACTTAACCG
CCATACTCCTATAGTTTTAATTAGTGCGAATGGCAGCGATGTGAATAGCATTGATTTAAAAAAATCAGGTGTGGATTTTT
GCTTGCAAAAACCTGTAGATGAAAAACAATTACTGACCCAAATCCTGCGGATTACCGATAAAGCTAAACATGCAGCAATT
GATTGGCAATTATGTGTGCAAAAAGTATCTGGAAATCAAGCACTTGCCGAAGAGTTTCTTAGCCGATTTGTAGAGGAATT
ACATAAAAATCGTGAAGAATTTATCCAATTAATGCATGATAAAAATATTAAAAAAATAGGCGAGGCAGCACATAAACTGC
ATGGAGCATGTTGTTTTTCTGGAGTGCCAACGCTACAGAAAAAAGTAGTCCAGGTAGAAAAACTGGCGGCACATGCCGCT
TCAATTGAAGAGCTCGCCACCCCTTTTGCCGAATTAATTCAAAGCATTGATGCTGTAATTAATGAATATGAACATCAAAA
AGTACGAATTTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (678-788)

• Hpt domain (Hpt) (818-900)

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

• Single cache domain 4 (sCache_4) (35-179)

3D structure

• AlphaFold DB: A0A0W0SAJ9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	79.801	99.56	0.795