Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ELZ63_RS07800 Genome accession   NZ_LR134171
Coordinates   1583056..1583730 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain NCTC12699     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1578056..1588730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ63_RS07780 (NCTC12699_01553) hinT 1579763..1580113 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  ELZ63_RS07785 (NCTC12699_01554) - 1580113..1580463 (+) 351 WP_005647993.1 DUF1425 domain-containing protein -
  ELZ63_RS07790 (NCTC12699_01555) nagZ 1580467..1581519 (+) 1053 WP_050837674.1 beta-N-acetylhexosaminidase -
  ELZ63_RS07795 (NCTC12699_01556) rlmC 1581516..1582691 (+) 1176 WP_065245151.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  ELZ63_RS07800 (NCTC12699_01557) crp 1583056..1583730 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  ELZ63_RS07805 (NCTC12699_01558) - 1583715..1583966 (-) 252 WP_005647999.1 YheU family protein -
  ELZ63_RS07810 (NCTC12699_01559) slmA 1583988..1584644 (-) 657 WP_061723804.1 nucleoid occlusion factor SlmA -
  ELZ63_RS07815 (NCTC12699_01560) dut 1584648..1585103 (-) 456 WP_005631431.1 dUTP diphosphatase -
  ELZ63_RS07820 (NCTC12699_01561) coaBC 1585151..1586353 (-) 1203 WP_065245150.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  ELZ63_RS07825 (NCTC12699_01562) radC 1586517..1587182 (+) 666 WP_013527272.1 DNA repair protein RadC -
  ELZ63_RS07830 (NCTC12699_01563) rpmB 1587397..1587633 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  ELZ63_RS07835 (NCTC12699_01564) rpmG 1587645..1587815 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=1118748 ELZ63_RS07800 WP_005647998.1 1583056..1583730(-) (crp) [Haemophilus influenzae strain NCTC12699]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1118748 ELZ63_RS07800 WP_005647998.1 1583056..1583730(-) (crp) [Haemophilus influenzae strain NCTC12699]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTACGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment