Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ELZ61_RS10450 Genome accession   NZ_LR134167
Coordinates   2189095..2190498 (+) Length   467 a.a.
NCBI ID   WP_126373460.1    Uniprot ID   A0A3S4H6I6
Organism   Avibacterium volantium strain NCTC3438     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2184095..2195498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ61_RS10425 (NCTC3438_02133) - 2184163..2186736 (-) 2574 WP_126373450.1 penicillin-binding protein 1A -
  ELZ61_RS10430 (NCTC3438_02134) - 2186895..2187695 (+) 801 WP_126373452.1 competence protein ComA -
  ELZ61_RS10435 (NCTC3438_02135) - 2187685..2188209 (+) 525 WP_126373454.1 hypothetical protein -
  ELZ61_RS10440 (NCTC3438_02136) - 2188190..2188729 (+) 540 WP_126373456.1 hypothetical protein -
  ELZ61_RS10445 (NCTC3438_02137) - 2188726..2189085 (+) 360 WP_126373458.1 pilus assembly protein PilP -
  ELZ61_RS10450 (NCTC3438_02138) comE 2189095..2190498 (+) 1404 WP_126373460.1 type IV pilus secretin PilQ Machinery gene
  ELZ61_RS10455 (NCTC3438_02139) aroK 2190634..2191182 (+) 549 WP_277870321.1 shikimate kinase AroK -
  ELZ61_RS10460 (NCTC3438_02140) aroB 2191203..2192291 (+) 1089 WP_126373689.1 3-dehydroquinate synthase -
  ELZ61_RS10465 (NCTC3438_02141) - 2192297..2193163 (+) 867 WP_126373465.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  ELZ61_RS10470 (NCTC3438_02142) - 2193151..2193465 (-) 315 WP_126373467.1 DciA family protein -
  ELZ61_RS10475 (NCTC3438_02143) secM 2193572..2193883 (+) 312 WP_126373469.1 secA translation cis-regulator SecM -

Sequence

Protein


Download         Length: 467 a.a.        Molecular weight: 51232.67 Da        Isoelectric Point: 8.7149

>NTDB_id=1118658 ELZ61_RS10450 WP_126373460.1 2189095..2190498(+) (comE) [Avibacterium volantium strain NCTC3438]
MRLLKCGAFFLSFSLFASASEKPSETFSIRLQQAPLVQTVQQLAAQQKVNLVIDDELQGSISLQLQQTTLAQFLQVVAKI
KQLQFWQENGIYYLSKAPQNSSPEVANNLPTEFVDTLPEPALPRLSTMTIKLHYAKASEVMKTLTSGSGSLLSANGSMSF
DDRSNLLIIKDEKAILNQMKRLVTEMDKPIEQIAIEARIVTISDESLKELGVRWGIFTPTDASHKVMGSLNANGFANITD
NLNVNFATTNTPAGSVALQIAKINGRLLDLELTALERENSVEIIASPSLLTTNKKSASIKQGTEIPYVVNNNKNDSQSIE
FREAVLGLEVTPHLSKNNGILLDLVVSQNAPGGRVAYGENEVIAIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
VLGDIPVIKRLFSKEVERHQKRELVIFVTPHLIKKGQQAEKQSAVKNPPKNHRTSSSSSKISHKSGK

Nucleotide


Download         Length: 1404 bp        

>NTDB_id=1118658 ELZ61_RS10450 WP_126373460.1 2189095..2190498(+) (comE) [Avibacterium volantium strain NCTC3438]
ATGCGATTATTAAAGTGCGGTGCGTTTTTTCTGAGTTTTTCATTATTTGCCAGCGCAAGCGAAAAACCAAGCGAAACCTT
TTCAATTCGCTTACAGCAAGCCCCTTTGGTACAGACCGTGCAACAGCTCGCAGCACAACAGAAGGTTAATTTAGTGATCG
ATGACGAATTGCAAGGTTCAATTTCGTTACAACTGCAACAAACAACCCTCGCGCAATTTTTGCAAGTGGTTGCCAAAATA
AAGCAGCTCCAATTCTGGCAGGAAAACGGTATTTATTATCTCAGTAAAGCCCCACAAAATTCTTCGCCAGAAGTAGCCAA
TAATCTTCCTACTGAATTTGTAGATACATTGCCTGAGCCAGCACTTCCCAGATTATCAACAATGACAATAAAATTGCACT
ATGCCAAAGCGTCTGAAGTGATGAAAACGCTCACTTCGGGCAGTGGCTCGTTGCTTTCAGCAAATGGCAGTATGAGTTTT
GATGATCGCAGTAACCTATTGATTATTAAAGATGAAAAAGCCATATTAAACCAAATGAAACGCTTGGTTACGGAAATGGA
TAAGCCCATTGAACAAATTGCTATTGAAGCGCGCATTGTTACTATTAGTGATGAAAGTTTGAAAGAACTTGGCGTGCGTT
GGGGGATTTTTACGCCAACAGATGCCAGCCATAAAGTAATGGGTAGCCTGAATGCGAATGGTTTTGCCAATATTACTGAT
AATCTCAACGTCAATTTCGCTACCACCAACACCCCAGCAGGCTCGGTGGCGTTGCAGATTGCCAAAATTAATGGAAGATT
GCTTGATTTAGAATTAACCGCCTTGGAGCGAGAAAATAGCGTAGAAATTATCGCTAGCCCAAGTTTGCTTACCACTAATA
AGAAAAGTGCGAGTATTAAGCAAGGGACGGAAATTCCTTATGTGGTGAATAATAATAAAAATGACAGCCAGAGCATTGAG
TTTCGCGAAGCGGTGCTGGGGCTAGAAGTAACGCCACATTTATCCAAAAATAACGGCATTTTGTTGGATTTGGTGGTGAG
CCAAAATGCCCCTGGTGGGCGTGTGGCTTATGGCGAAAACGAAGTCATTGCTATTGATAAGCAAGAAATTAACACGCAAG
TTTTTGCACAAGATGGGGAAACCATTGTGCTAGGTGGTATCTTTCACGATACCATTACCAAAGCCTTAGATAAAGTGCCT
GTGCTGGGTGATATTCCTGTGATTAAACGCTTGTTTAGTAAAGAAGTAGAGCGTCATCAAAAACGGGAATTGGTGATTTT
CGTCACACCGCATTTGATCAAAAAAGGGCAACAGGCCGAAAAACAAAGTGCGGTGAAAAATCCGCCAAAAAATCACCGCA
CTTCGTCATCTTCTAGCAAGATTTCGCACAAATCTGGTAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(274-434)

Bacterial type II/III secretion system short domain (Secretin_N)

(127-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S4H6I6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

67.873

94.647

0.642
  comE Haemophilus influenzae 86-028NP

67.195

94.647

0.636
  comE Glaesserella parasuis strain SC1401

51.121

95.503

0.488
  pilQ Vibrio campbellii strain DS40M4

39.12

92.505

0.362

Multiple sequence alignment