Detailed information NTG1117245

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EJ099_RS24780
• Genome accession: NZ_LR130536
• Coordinates: 5230721..5232058 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate paerg010
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5225721..5237058

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJ099_RS24755 (BANRA_04806)	pgeF	5225864..5226592 (-)	729	WP_014603307.1	peptidoglycan editing factor PgeF	-
EJ099_RS24760 (BANRA_04807)	rluD	5226589..5227551 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EJ099_RS24765 (BANRA_04808)	-	5227697..5228722 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EJ099_RS24770 (BANRA_04809)	-	5228879..5229124 (+)	246	WP_014603308.1	PP0621 family protein	-
EJ099_RS24775 (BANRA_04810)	pilS	5229114..5230706 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
EJ099_RS24780 (BANRA_04811)	pilR	5230721..5232058 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EJ099_RS24785 (BANRA_04812)	thiO	5232104..5233198 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
EJ099_RS24790 (BANRA_04813)	-	5233333..5233842 (+)	510	WP_003161431.1	GspH/FimT family pseudopilin	-
EJ099_RS24795 (BANRA_04814)	-	5233948..5234454 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
EJ099_RS24800 (BANRA_04815)	pilV	5234445..5235002 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EJ099_RS24805 (BANRA_04816)	pilW	5234999..5235823 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EJ099_RS24810 (BANRA_04817)	pilX	5235820..5236407 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1117245 EJ099_RS24780 WP_003094694.1 5230721..5232058(+) (pilR) [Pseudomonas aeruginosa isolate paerg010]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1117245 EJ099_RS24780 WP_003094694.1 5230721..5232058(+) (pilR) [Pseudomonas aeruginosa isolate paerg010]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384