Detailed information NTG1117078

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: EJM92_RS11950
• Genome accession: NZ_LR130531
• Coordinates: 2548448..2549785 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa isolate paerg004
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 2543448..2554785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJM92_RS11925 (BANRA_02315)	pgeF	2543591..2544319 (-)	729	WP_014603307.1	peptidoglycan editing factor PgeF	-
EJM92_RS11930 (BANRA_02316)	rluD	2544316..2545278 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
EJM92_RS11935 (BANRA_02317)	-	2545424..2546449 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
EJM92_RS11940 (BANRA_02318)	-	2546606..2546851 (+)	246	WP_014603308.1	PP0621 family protein	-
EJM92_RS11945 (BANRA_02319)	pilS	2546841..2548433 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
EJM92_RS11950 (BANRA_02320)	pilR	2548448..2549785 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
EJM92_RS11955 (BANRA_02321)	thiO	2549831..2550925 (-)	1095	WP_020750388.1	glycine oxidase ThiO	-
EJM92_RS11960 (BANRA_02322)	-	2551060..2551569 (+)	510	WP_003161431.1	GspH/FimT family pseudopilin	-
EJM92_RS11965 (BANRA_02323)	-	2551675..2552181 (+)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
EJM92_RS11970 (BANRA_02324)	pilV	2552172..2552729 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
EJM92_RS11975 (BANRA_02325)	pilW	2552726..2553550 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
EJM92_RS11980 (BANRA_02326)	pilX	2553547..2554134 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1117078 EJM92_RS11950 WP_003094694.1 2548448..2549785(+) (pilR) [Pseudomonas aeruginosa isolate paerg004]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1117078 EJM92_RS11950 WP_003094694.1 2548448..2549785(+) (pilR) [Pseudomonas aeruginosa isolate paerg004]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384